Figure 9.

Hsp/hsc70 inhibition alters the properties of DEM-SGs. (A) HeLa cells were incubated with 2 mM DEM for 4 hours. The vehicle DMSO or 10 µM apoptozole were added together with ethanol (EtOH) or DEM. Scale bar is 20 μm. (B,C) Quantification is shown as average + SEM for two independent experiments. Results were normalized to vehicle controls. At least 54 cells or 355 SGs were evaluated for each experiment and data point. Significant differences were identified with Student’s t-test; *** p < 0.001. AU, arbitrary units.