aDepartment of Allergy and Clinical Immunology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, National Clinical Research Center for Immunologic Diseases, Beijing, 100730, China
bCenter for Systems Medicine, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100005, China
cSuzhou Institute of Systems Medicine, Suzhou, Jiangsu, 215123, China
dDepartment of Respiratory Diseases, The Second Medical Center and National Clinical Research Center for Geriatric Diseases, Chinese PLA General Hospital, Beijing, 100853, China
eDepartment of Ophthalmology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong 999077, China
fDepartment of Infection Prevention and Disease Control, The Second Medical Center and National Clinical Research Center for Geriatric Diseases, Chinese PLA General Hospital, Beijing, 100853, China
gDivision of Rheumatology, Allergy and Clinical Immunology, University of California, Davis, CA, 95616, USA
hDivision of Pediatric Immunology and Allergy, Joe DiMaggio Children's Hospital, Hollywood, FL, USA
∗Corresponding author. University of California, 451 Health Sciences Drive, Suite 6510, Davis, CA, 95616, USA.
∗∗Corresponding author. No.1 Shuaifuyuan Wangfujing Dongcheng District, Beijing, 100730, China.
∗∗∗Corresponding author. No. 28 Fuxing Road, Beijing, 100853, China.
∗∗∗∗Corresponding author. No. 9 Dongdan 3rd, Dongcheng District, Beijing, 100005, China.
1These authors contributed equally to this work.