Table 3.
Treatment | ΔcmeB | ΔcmeR | ΔcmeF | ΔcmeG | ||||
---|---|---|---|---|---|---|---|---|
MIC (mg/L) | FCa | MIC (mg/L) | FCa | MIC (mg/L) | FCa | MIC (mg/L) | FCa | |
Ethanolic extract | 31.25 | 4 | 125 | 1 | 62.5 | 2 | 31.25 | 4 |
Essential oil | 1000 | 1 | 1000 | 1 | 1000 | 1 | 500 | 2 |
Carvacrol | 15.25 | 2 | 7.81 | 4 | 15.62 | 2 | 0.97 | 32 |
Thymol | 7.81 | 4 | 7.81 | 4 | 31.25 | 1 | 1.95 | 16 |
Thymoquinone | 15.25 | 2 | 7.81 | 4 | 15.62 | 2 | 0.97 | 32 |
p-cymene | 1000 | 1 | 500 | 2 | 500 | 2 | 500 | 2 |
γ-terpinene | 500 | 2 | 250 | 4 | 250 | 4 | 500 | 2 |
Rosmarinic acid | 62.5 | 4 | 125 | 4 | 125 | 2 | 125 | 2 |
aFC, Fold change increase in antimicrobial activity of the tested compound in the mutant strain, compared to wild type.