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. 2020 Apr 24;8(4):95. doi: 10.3390/biomedicines8040095

Table 2.

Median 12-item Short Form Survey (SF-12) component scores by patients’ characteristic variables.

Variable n Score of PCS-12 Median (min–max) p-Value Score of MCS-12 Median (max–min) p-Value
All the sample 20 53.6 (43.7–60.6) 28.6 (19.6–37.9)
Age 0.06 0.018
 Under 60 4 48.8 (44.5–53.4) 31.9 (29.9–35.2)
 Over 60 16 56.2 (43.7–60.6) 27.4 (19.6–37.97)
Gender 0.70 0.22
 Male 8 54.02 (43.7–60.3) 28.789 (26.2–37.97)
 Female 12 54.5 (44.5–60.6) 27.4 (19.6–35.2)
Marital status 0.71 0.58
 Single 5 54.7 (43.8–60.1) 27.5 (25.4–37.97)
 Married 14 54.5 (44.5–60.6) 27.7 (19.6–35.2)
 Not declared 1 53.4 30.8
Tumor 0.28 0.68
 Cancer 8 57.4 (50.2–60.1) 27.7 (24.4–29.7)
 Cancer with bone metastasis 12 52.96 (44.5–60.6) 28.6 (19.6–37.97)
Anti-resorptive medication timing 0.86 0.73
 Past 15 53.5 (43.7–60.6) 27.9 (19.6–37.97)
 Current 5 57.1 (45–60.1) 27.4 (25.4–35.2)
Active principle 0.57 0.54
 Zoledronic acid 9 54.7 (43.7–60.6) 27.5 (19.6–37.97)
 Clodronic acid 1 57.1 28.8
 Alendronic acid 1 60.1 25.4
 Denosumab (one dose every month) 3 57.8 (50.8–60.3) 27.9 (26.5–29.8)
 Adalimumab 1 53.5 23.6
 Combination 5 50.2 (45–59.4) 29.7 (26.3–35.2)
Method of administration 0.38 0.38
 I.V 11 53.4 (43.7–60.6) 27.5 (19.6–37.97)
 I.M/S.C 5 57.1 (50.8–60.3) 27.9 (23.6–29.8)
 Oral 1 60.1 25.4
 Association 3 52.6 (45–59.4) 32.99 (27.4–35.2)
Anti-resorptive medications duration 0.25 0.45
 <3 years 8 57.1 (50.2–60.3) 29.3 (26.6–37.97)
 >3 years 12 51.7 (47.7–60.6) 28.1 (19.6–35.2)
 I.V < 8 infusions 2 57.4 (55.4–59.4) 25.9 (24.4–27.4)
 I.V + 8 infusions 12 51.4 (43.7–60.6) 29.8 (19.6–37.97)
MRONJ stage 0.85 0.15
 0 6 53.4 (46.8–60.1) 27.5 (23.6–30.8)
 I 2 51.4 (45–57.7) 31.4 (27.5–35.2)
 II 11 55.4 (43.7–60.6) 27.4 (19.6–34.5)
 III 1 54.7 37.97
Localization 0.47 1.00
 Maxilla 3 54.1 (43.7–60.3) 27.438 (23.6–37.97)
 Mandible 12 57.8 (45–60.6) 27.9 (19.6–35.2)
 Both 5 54.3 (46.8–60.1) 28.2 (25.4–30.8)