Figure 6.

(A) Protein and RNP complexes at the chromosome ends. Whereas the shelterin complex binds to protect the chromosome ends, telomerase as well as the CST complex act on the G-rich or C-rich strand, respectively, to facilitate their synthesis. (B) Cryo-EM-based model structure of the human telomerase holoenzyme, taken from [63]. Copyright of Figure 6B by Wang et al. is with CSHP—Copyright for use has been requested from the publisher.