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. 2020 Apr 30;25(9):2114. doi: 10.3390/molecules25092114

Table 3.

Ethno-medicinal plants influencing the ACE2 pathway.

Species Mechanism Bioactive Phytochemicals Geographical Distribution Reference
Qishenyiqi
(Radix Astragali Mongolici, salvia miltiorrhiza bunge, Flos Lonicerae, scrophularia, Radix Aconiti Lateralis Preparata, Radix Glycyrrhizae)
Blocks effect of Ang II by acting on AT1R and AT2
RIncreases ACE2
Not known East Asia Wang, et al. [75]
Rosmarinus officinalis Linn. Decreases ACE expression and increases ACE2 expression, decreases expression of AT1R Rosmarinic acid Mediterranean region, but widely cultivated Liu, et al. [76]
Scutellaria baicalensis Enhances ACE2 protein expression Flavonoids (Baicalin) North America Zhang, et al. [77]