Cell motility according to the wound-healing assay of human oral cancer cells following sesamin treatment. (a) FaDu cells were seeded into 6-well plates in appropriate numbers. Photographs show wound closure following treatment with sesamin (SES) (0, 10, 20, or 40 μM) for 4 and 8 h. (b) The quantitative analysis shows the FaDu cell movement distance. (c) HSC-3 cells shown at the different time points of 2, 4, and 8 h by wound closure photographs and (d) the quantitative results. (e,f) Ca9-22 cells shown at 3, 6, 24 h by wound closure photographs. The values represent the means ± SD of at least three independent experiments. * p < 0.05, compared with the control group.