Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Inhibition of falcipains 2, 3 and various strains of P. falciparum by gallinamide A analogues 32–36 (IC50 nM).
| Compound | Falcipain | P. falciparum | |||
|---|---|---|---|---|---|
| 2 | 3 | 3D7 | Dd2 | W2 | |
| 32 | 5.25 | 81.4 | 20.0 | 67.0 | |
| 33 | 12.0 | 66.7 | 9.7 | 29.0 | |
| 34 | 31.0 | 117.0 | 26.0 | 28.0 | |
| 35 | 29.0 | 79.0 | 42.0 | 49.0 | |
| 36 | 33.0 | 112.0 | 1.0 | 4.0 | |
