Figure 1. Overview of the processing steps involved in FBA and VBA whole-brain analyses.
(A) Processing steps for fixel-based analysis (FBA) and voxel-based analysis (VBA). Processing steps specific to FBA are shown on the left; those specific to VBA, on the right. (B) Illustration of the derived FBA and VBA metrics. DWI = diffusion-weighted imaging; FA = Fractional anisotropy; FC = fiber cross-section; FD = fiber density; FDC = fiber density and cross section combined; FOD = fiber orientation distribution; MD = mean diffusivity.