Francisco Esteves
Francisco Esteves
1Centre for Toxicogenomics and Human Health (ToxOmics), Genetics, Oncology and Human Toxicology, NOVA Medical School, Faculty of Medical Sciences, Universidade NOVA de Lisboa, Lisbon, Portugal
1,*,
Diana Campelo
Diana Campelo
1Centre for Toxicogenomics and Human Health (ToxOmics), Genetics, Oncology and Human Toxicology, NOVA Medical School, Faculty of Medical Sciences, Universidade NOVA de Lisboa, Lisbon, Portugal
1,
Bruno Costa Gomes
Bruno Costa Gomes
1Centre for Toxicogenomics and Human Health (ToxOmics), Genetics, Oncology and Human Toxicology, NOVA Medical School, Faculty of Medical Sciences, Universidade NOVA de Lisboa, Lisbon, Portugal
1,
Philippe Urban
Philippe Urban
2Centre National de la Recherche Scientifique, Institut National de la Recherche Agronomique, Institut National des Sciences Appliquées de Toulouse, Toulouse Biotechnology Institute, Université de Toulouse, Toulouse, France
2,
Sophie Bozonnet
Sophie Bozonnet
2Centre National de la Recherche Scientifique, Institut National de la Recherche Agronomique, Institut National des Sciences Appliquées de Toulouse, Toulouse Biotechnology Institute, Université de Toulouse, Toulouse, France
2,
Thomas Lautier
Thomas Lautier
2Centre National de la Recherche Scientifique, Institut National de la Recherche Agronomique, Institut National des Sciences Appliquées de Toulouse, Toulouse Biotechnology Institute, Université de Toulouse, Toulouse, France
2,
José Rueff
José Rueff
1Centre for Toxicogenomics and Human Health (ToxOmics), Genetics, Oncology and Human Toxicology, NOVA Medical School, Faculty of Medical Sciences, Universidade NOVA de Lisboa, Lisbon, Portugal
1,
Gilles Truan
Gilles Truan
2Centre National de la Recherche Scientifique, Institut National de la Recherche Agronomique, Institut National des Sciences Appliquées de Toulouse, Toulouse Biotechnology Institute, Université de Toulouse, Toulouse, France
2,
Michel Kranendonk
Michel Kranendonk
1Centre for Toxicogenomics and Human Health (ToxOmics), Genetics, Oncology and Human Toxicology, NOVA Medical School, Faculty of Medical Sciences, Universidade NOVA de Lisboa, Lisbon, Portugal
1,*
1Centre for Toxicogenomics and Human Health (ToxOmics), Genetics, Oncology and Human Toxicology, NOVA Medical School, Faculty of Medical Sciences, Universidade NOVA de Lisboa, Lisbon, Portugal
2Centre National de la Recherche Scientifique, Institut National de la Recherche Agronomique, Institut National des Sciences Appliquées de Toulouse, Toulouse Biotechnology Institute, Université de Toulouse, Toulouse, France
Edited and reviewed by: Miia Turpeinen, Oulu University Hospital, Finland
✉*Correspondence: Francisco Esteves, francisco.esteves@nms.unl.pt; Michel Kranendonk, michel.kranendonk@nms.unl.pt
This article was submitted to Drug Metabolism and Transport, a section of the journal Frontiers in Pharmacology
Received 2020 Apr 1; Accepted 2020 May 11; Collection date 2020.
Keywords: NADPH cytochrome P450 oxidoreductase (CPR), cytochrome P450 monooxygenases (CYP), FMN-domain, binding motifs, redox partner, protein–protein interaction, electron transfer
Copyright © 2020 Esteves, Campelo, Gomes, Urban, Bozonnet, Lautier, Rueff, Truan and Kranendonk
This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.