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[Preprint]. 2020 Jul 31:2020.05.04.075291. Originally published 2020 May 5. [Version 2] doi: 10.1101/2020.05.04.075291

Figure 1. Baseline levels of cytotoxic lymphocytes inversely correlate with ACE2 expression in the lung.

Figure 1.

(a-c) The correlations between the baseline levels of CD8+ T cells, resting NK cells and activated NK cells (x-axes) and the those of the SARS-CoV-2 host cell receptor ACE2 (y-axes) in human lung tissue are shown. Data are from the GTEx dataset (n=578). (d-f) The same correlations are shown for lung tissues in the LUG dataset (n=1,349). Regression lines and 95% confidence intervals are shown. R and p values: Pearson correlations; q values: Benjamini-Hochberg-adjusted p values using a false discovery rate of 0.05; mp values: multivariate p values (see Table S3).