Table 1.
Length of infection | HPV type1 | Single-type HPV infections2 |
|||||||
---|---|---|---|---|---|---|---|---|---|
Frequency | CIN3+ cases3 |
Cumulative risk of CIN3+ (%) |
|||||||
Total | Detected at baseline | Yr 0 | Yr 1 | Yr 3 | Yr 5 | Yr 7 | |||
Prevalent | 16 | 1907 | 664 | 430 | 18.2 | 20.4 | 23.3 | 24.1 | 24.7 |
33 | 130 | 42 | 28 | 16.1 | 18.7 | 20.0 | 20.5 | 20.9 | |
18 | 520 | 102 | 60 | 8.1 | 9.0 | 10.2 | 10.9 | 11.0 | |
58 | 324 | 60 | 46 | 8.4 | 9.1 | 10.0 | 10.6 | 10.8 | |
31 | 949 | 149 | 89 | 6.7 | 7.4 | 8.9 | 9.3 | 9.4 | |
35 | 261 | 39 | 19 | 5.5 | 7.0 | 7.9 | 8.8 | 9.1 | |
52 | 1073 | 130 | 73 | 4.6 | 5.2 | 6.5 | 6.7 | 6.9 | |
45 | 371 | 50 | 35 | 5.3 | 5.7 | 6.3 | 6.7 | 6.8 | |
39 | 268 | 20 | 13 | 2.7 | 3.2 | 3.8 | 3.9 | 3.9 | |
56 | 253 | 14 | 11 | 2.2 | 2.2 | 2.4 | 2.6 | 2.7 | |
51 | 603 | 30 | 15 | 1.6 | 1.9 | 2.5 | 2.6 | 2.6 | |
68 | 174 | 7 | 3 | 0.8 | 1.3 | 1.9 | 2.1 | 2.1 | |
59 | 189 | 8 | 4 | 1.3 | 1.6 | 1.9 | 2.0 | 2.0 | |
Prevalent Total | 7022 | 1315 | 826 (62.8%) | ||||||
Incident | 16 | 472 | 87 | 42 | 6.2 | 7.8 | 9.6 | 10.8 | 10.9 |
33 | 44 | 8 | 5 | 7.6 | 9.2 | 11.0 | 11.1 | 11.1 | |
18 | 176 | 27 | 16 | 5.6 | 6.2 | 7.1 | 7.8 | 7.9 | |
58 | 91 | 6 | 6 | 3.3 | 3.3 | 3.3 | 3.3 | 3.3 | |
31 | 299 | 21 | 10 | 2.4 | 2.6 | 3.0 | 3.4 | 3.5 | |
35 | 71 | 5 | 4 | 3.8 | 3.8 | 3.8 | 3.8 | 3.8 | |
52 | 321 | 15 | 8 | 1.6 | 1.7 | 2.2 | 2.4 | 2.4 | |
45 | 143 | 11 | 5 | 2.2 | 2.4 | 3.1 | 3.8 | 4.0 | |
39 | 85 | 5 | 3 | 2.1 | 2.5 | 2.8 | 2.8 | 2.8 | |
56 | 103 | 3 | 0 | 0.0 | 0.7 | 0.9 | 0.9 | 1.2 | |
51 | 287 | 10 | 3 | 0.7 | 0.9 | 1.4 | 1.6 | 1.7 | |
68 | 55 | 4 | 3 | 3.4 | 3.4 | 3.4 | 3.4 | 3.4 | |
59 | 66 | 2 | 0 | 0.0 | 0.1 | 0.8 | 1.6 | 1.8 | |
Incident Total | 2213 | 204 | 105 (51.5%) | ||||||
All infections | Total | 9235 | 1519 | 931 (61.2%) |
Ordered based on descending risk of CIN3+ for prevalent (most common) single type infections.
Risk estimates restricted to single-type HPV infections.
Average time to end of follow-up was 4.1 years for prevalent infections and 4.9 years for incident ones.