Table 2.

Baseline PROMIS scores

Measure	Baseline Mean (SD)
PROMIS Global Health
-Physical Health Summary Score	42.5 (12.1)
-Mental Health Summary Score	48.5 (9.4)
Individual domains
-Anxiety	55.5 (8.7)
-Depression	53.4 (9.2)
-Fatigue	55.6 (12.2)
-Pain Interference	51.2 (10.9)
-Physical Function	39.8 (10.8)
-Sleep disturbance	51.8 (9.9)
-Ability to Participate in Social roles and Activities	47.1 (10.9)

Score interpretation: Higher scores indicate more of the concept being measured. For the domains of Anxiety, Depression, Fatigue (derived from Fatigue 8a), Pain, Sleep Disturbance, a higher score represents greater symptom; Physical Function, Ability to Participate in Social Roles and Activities, Global Physical Health, Global Mental Health: higher score represents better function

PROMIS scores are represented on the T-score metric (mean = 50, standard deviation (SD) = 10), scaled so that a score of 50 corresponds to the mean of the reference population; for most PROMIS domains the reference population is the general U.S. adult population, though for 2 domains in the PROMIS-29, Ability to Participate in Social Roles and Activities and Sleep Disturbance, the calibration sample included more people with chronic illness.