Table 4.
Correlation among PROMIS scales
| Correlations between PROMIS Global Health, PROMIS-29, and Fatigue-8 in AL amyloidosis | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Global PH | Global MH | Anxiety | Depression | Fatigue | Pain | Physical Function | Sleep Disturbance | Social Roles | |
| Global PH | 1.00 | 0.74 | −0.45 | −0.60 | −0.86 | −0.55 | 0.86 | −0.32 | 0.77 |
| Global MH | 1.00 | −0.68 | −0.73 | −0.62 | −0.60 | 0.59 | −0.38 | 0.75 | |
| Anxiety | 1.00 | 0.79 | 0.46 | 0.45 | −0.37 | 0.40 | −0.41 | ||
| Depression | 1.00 | 0.64 | 0.40 | −0.46 | 0.40 | −0.49 | |||
| Fatigue | 1.00 | 0.51 | −0.77 | 0.39 | −0.72 | ||||
| Pain | 1.00 | −0.42 | 0.36 | −0.56 | |||||
| Physical Function | 1.00 | −0.29 | 0.75 | ||||||
| Sleep Disturbance | 1.00 | −0.35 | |||||||
| Social Role | 1.00 | ||||||||
| Correlations within PROMIS Global Health Scale in AL amyloidosis | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Global 03 | Global 06 | Global 07 | Global 08 | Global PH | Global 02 | Global 04 | Global 05 | Global 10 | Global MH | ||
| Global 03 | 1.00 | 0.74 | 0.46 | 0.70 | 0.87 | Global 02 | 1.00 | 0.62 | 0.63 | 0.33 | 0.83 |
| Global 06 | 1.00 | 0.35 | 0.77 | 0.87 | Global 04 | 1.00 | 0.48 | 0.50 | 0.82 | ||
| Global 07 | 1.00 | 0.45 | 0.66 | Global 05 | 1.00 | 0.31 | 0.81 | ||||
| Global 08 | 1.00 | 0.89 | Global 10 | 1.00 | 0.67 | ||||||
| Global PH | 1.00 | Global MH | 1.00 | ||||||||
Fatigue is derived from Fatigue 8a
Interpretation: The numbers in the boxes signify Pearson’s correlation coefficients; Score 0.1–0.29- weak, 0.3–0.49- medium and ≥0.5- strong correlations. Positive numbers signify correlation in the same direction and negative indicate correlation in opposite directions. e.g. the domains of Depression and Fatigue have a Pearson correlation coefficient of 0.64 implying a strong positive relation between the 2 domains, while Fatigue and Social Roles have a Pearson correlation coefficient of −0.72 implying a strong negative correlation between the 2 domains
Global PH- PROMIS Global Physical Health Summary Score (sum of global 03, 06, 07 and 08); Global MH- PROMIS Mental Health Summary Score (sum of global 02, 04, 05, 10).
Global 03- Physical health; Global 06- Physical function; Global 07- Pain; Global 08- Fatigue
Global 02- Quality of life; Global 04- Mental health; Global 05- Satisfaction with social activites; Global 10- Emotional problems