Table A.2.

Summary of parameters and their interpretation. All time rate constants are in units of day ^{− 1}. Parameters are known from previous studies, set for each scenario, or calibrated to match the model to past outbreaks.

Parameter	Interpretation	Type	Range and Sources, if available
b0	Core transmission rate	Calibrated	See section on model calibration
bh	Relative contact rate during weekends	Calibrated	0 to 0.5, comparable to school closure in [18]
bc	Relative contact rate during closures, holidays or vacations	Calibrated	Generally lying around 0 to 0.5 comparable to school closure in [18]
bs	Relative seasonal amplitude of contact	Calibrated
ci, j	Relative contact rate for cohorts i and j	Input data or calibrated	Sometimes estimated from locations of cohorts in a building
L	Symptomatic rate	Input data	0.88 [59], 0.5 and 0.88 for COVID-19
p	Fraction of persons complying with policy	Calibrated	Quantifies compliance with the policy
rd	Fraction of persons return to cohort on day d after infection	Based on symptom data	See table below
sd	Shedding at day d (relative)	Input data or estimates	Proportional to log 10 titers [14]
tstart	Day of first infected case	Input data or calibration	Often reported approximately in post-outbreak investigations
v	Vaccination rate (seasonal virus)	Set during scenarios	Season flu: 60% [0.5, 0.7] [60], 0% in novel infections
ve	Vaccine efficacy (seasonal vims)	67% [0.65, 0.95]	[61,62] For novel infections with no immune response, 0%
Xi	Persons in cohort i	Set by scenario	Cohort is partitioned into fraction vve with vaccine protection and the rest
y	Fever attention	Calibrated	Fraction of persons who would return from home, of those having symptoms on the previous day