Figure 5.

Changes in wound area at each time point to the original wound area of mice in control and treatment group over a period of 12 days. A; Wound healing area (mm²) of test groups, B; Wound healing percentages (%) of test and control groups, C; Digital photographs of mice showing various stages of wound healing. Day 0 picture was taken immediately after injury. Values of diameter of wounds are expressed as mean ± SEM (n = 12). a = when compared with control group, (∗) indicates statistically significant difference from respective group using ANOVA, followed by Tukey's comparisons test (p > 0.05). (†) indicates statistically no significant difference from respective group using ANOVA, followed by Tukey's comparisons test (p > 0.05). Control group received an equal volume of distilled water, orally; untreated wounds and Treatment group received S. illicifolium extracts (400 mg/kg BW/day for 12 days, orally).