Table 1.
Results from replication using an independent case-control cohort of sporadic migraineurs and controls. The table presents the name and MAF of the index SNP of the migraine risk loci, as given by Gormley et al. (2016) [6], the genomic positions of the regulatory regions, the type of regulatory regions, the Bonferroni-corrected p values, and the ORs with the 95% confidence intervals (CI)
| Locus | MAF | Position (chromosome:start:end) | Type | p value | OR (95% CI) |
|---|---|---|---|---|---|
| PHACTR1 | 0.41 | chr6:13486092:13488560 | CpG island | 5.3·10−15 | 1.54 (1.44–1.65) |
| KCNK5 | 0.28 | chr6:39310446:39312846 | PRE | 0.014 | 1.24 (1.1–1.39) |
| ASTN2 | 0.36 | chr9:116284900:116285300 | PRE | 0.017 | 1.5 (1.18–1.9) |
| RNF213 | 0.17 | chr17:79742606:79746206 | PRE | 9.3·10−5 | 1.12 (1.07–1.18) |