Table 4.
Behavioural tests.
| Open Field | ||||||
|---|---|---|---|---|---|---|
| 12 Weeks | 16 Weeks | 20 Weeks | ||||
| Parameters | LZRs (n = 6) | OZRs (n = 6) | LZRs (n = 6) | OZRs (n = 6) | LZRs (n = 6) | OZRs (n = 6) |
|
Tot.
Dist. Trav. (cm) |
2741.6 ± 221.9 | 1307.4 ± 95.2 * | 2160.1 ± 101.3 | 1100.1 ± 87.3 * | 1910.9 ± 151.5 | 1009.2 ± 66.4 * |
|
Tot.
Amb. Cnts |
1870.6 ± 156.2 | 764.3 ± 62.8 * | 1956.0 ± 113.4 | 876.7 ± 90.5 * | 1667.8± 142.5 | 789.5 ± 62.4 * |
|
Tot.
Vert. Cnts |
94.4 ± 6.9 | 39.3 ± 3.7 * | 78.3 ± 2.6 | 37.7 ± 5.2 * | 83.5 ± 4.6 | 37.5 ± 4.5 * |
| Central Zone. Dist. Trav. | 229.3 ± 7.6 | 103.3 ± 26.7 * | 264.4 ± 22.6 | 91.9 ± 21.9 * | 224.1 ± 36.1 | 56.1 ± 7.8 * |
| Central zone Entries | 159.5 ± 9.7 | 60.2 ± 13.1 * | 103.2 ± 9.8 | 34.5 ± 9.5 * | 89.0 ± 12.1 | 21.5 ± 3.5 * |
| % Dist. Trav. | 8.6 ± 0.6 | 8.4 ± 2.3 | 12.1 ± 0.5 | 9.2 ± 2.9 | 11.8 ± 2.0 | 5.7 ± 0.9 * |
| Passive Avoidance | ||||||
|
Latency time
72 h after electric shock (s) |
176.3 ± 33.2 | 174.8 ± 30.7 | 171.3 ± 32.8 | 169.8 ± 30.8 | 177.3 ± 46.2 | 47.7 ± 16.2 * |
Tot. Dist.Trav.: total distance travelled; Tot. Amb. Cnts: number of movements; Tot. Vert. Cnts: number of rearing; Central Zone Dist. Trav.: distance travelled on central zone; Central Zone Entries: number of entrances in the central zone; % Dist. trav: percentage ratio between the distance travelled in the central zone and the total area; Data are the mean ± SEM. * p < 0.05 vs. age-matched LZRs.