Table 6.

Pharmacokinetic data from the curve fitting of in vivo rabbit plasma data after administration of the optimized formulation and the marketed products (n = 6) with SD.

	tmax (h)	t1/2 (h)	Cmax (μg/mL)	AUC(0-8) (μg.h/mL)	MRT (h)
Optimized FEX EIFV	1.00 *	1.75 * ± 0.41	53.94 * ± 6.09	212.22 * ± 8.77	3.25 * ± 0.33
Marketed product	3.00	2.39 ± 0.36	37.28 ± 3.54	177.89 ± 8.16	3.89 ± 0.24

Abbreviations: (AUC) the area under the curve, (MRT) the mean residence time, (SD) the standard deviation. * Significant difference (p < 0.05).