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. 2020 May 19;12(5):463. doi: 10.3390/pharmaceutics12050463

Table 3.

Percentage of entrapment efficiency (EE) and loading capacity (LC) of chili extract-loaded SLN and NLC prepared by the high-pressure homogenization method.

Capsaicin Conc. (%) Formulation Lipid Phase (Wax) % EE % LC
0.075 SLN GBH + COH + chili 78.33 ± 0.25 2.35 ± 0.01
GMS + COH + chili 82.23 ± 1.69 2.47 ± 0.05
GBH + SOH + chili 77.27 ± 5.98 2.32 ± 0.18
GMS + SOH + chili 76.49 ± 8.85 2.29 ± 0.27
NLC GBH + COH + IPM + chili 85.99 ± 6.37 2.58 ± 0.19
GMS + COH + IPM + chili 91.67 ± 4.02 2.75 ± 0.12
GBH + SOH + IPM + chili 84.65 ± 3.01 2.54 ± 0.09
GMS + SOH + IPM + chili 85.43 ± 1.29 2.56 ± 0.04
0.25 SLN GMS + COH + chili 68.63 ± 0.54 6.86 ± 0.05
NLC GMS + COH + IPM + chili 85.27 ± 0.12 8.53 ± 0.01

Abbreviations: SLN, solid lipid nanoparticles; NLC, nanostructured lipid carriers; GBH, Glyceryl behenate; GMS, Glyceryl monostearate; COH, cetyl alcohol; SOH, stearyl alcohol; IPM, isopropyl myristate.