CORRIGENDUM for “Central Adrenal Insufficiency Is Rare in Adults With Prader–Willi Syndrome”

In the above-named article by Rosenberg AGW, Pellikaan K, Poitou C, Goldstone AP, Høybye C, Markovic T, Grugni G, Crinò A, Caixàs A, Coupaye M, Van Den Berg SAA, Van Der Lely AJ, and De Graaff LCG (J Clin Endocrinol Metab. 2020;105(7):1–9; doi: 10.1210/clinem/dgaa168), the following errors occurred in Table 3. Results of the insulin tolerance test:

Table 3.

Results of the insulin tolerance test

	Baseline Cortisol (nmol/L)	Peak Cortisol (nmol/L)	Glucose (mmol/L)a	Baseline ACTH (pmol/L)	Peak ACTH (pmol/L)	Delta ACTH (pmol/L)b	CAI Cut-off (nmol/L)c
France (n = 10)
Median	229.0	735.5	1.6	N/A	N/A	N/A	<500
Range	102.0–384.0	494.0–1021.0	0.6–2.2	N/A	N/A	N/A
The Netherlands (n = 10)
Median	233.0	702.0	1.9	3.3	61.2	57.1	<500
Range	119.0–502.0	530.0–883.0	1.4–2.4	1.1–6.2	23.8–93.5	21.2–90.5
Sweden (n = 6)
Median	185.5	722.5	1.7	N/A	N/A	N/A	<500
Range	175.0–265.0	502.0–822.0	1.2–2.6	N/A	N/A	N/A
United Kingdom (n = 10)
Median	172.5	522.5	1.5	3.7	N/A	N/A	<450
Range	93.0–545.0	455.0–971.0d	1.0–2.1	1.7–6.4	N/A	N/A

Abbreviations: CAI, central adrenal insufficiency. N/A, not available.

^a Two patients had glucose levels of 2.4 mmol/L and 2.6 mmol/L, respectively. All other patients had glucose levels ≤ 2.2 mmol/L. ^b Increase in ACTH after insulin administration. ^c Peak cortisol cutoff for diagnosis of CAI. One French patient had peak cortisol < 500 nmol/L. ^d In the UK, the cutoff for CAI is 450 nmol/L (see also: methods).

For the UK cohort, the values in the column “Baseline ACTH (pmol/L)” are incorrect. The correct median is 3.7 pmol/L instead of 17.5 pmol/L and the correct range is 1.7–6.4 pmol/L instead of 93.0–545.0 pmol/L.

Additionally, a superscript “a” after the range in the column “Peak cortisol (nmol/L)” for the UK cohort should not have appeared in the published table. The full corrected table is below: