Figure 2.

Bland–Altman plots (top) and corresponding test/retest (TT/RT) mean distributions (bottom) are shown (left-to-right) for: (A, B) 15th, 25th, and 50th ADC percentiles; (C, D) low ADC volumes, V_ADC, thresholded at ADC < 0.9, 1.1, and 1.3 μm²/ms; and (E, F) fractional volumes, fV_ADC (V_ADC normalized by total histogram volume V_3.0). The 95% limits of agreement for mean metrics are shown by dashed lines. The symbol and line assignments are color-coded in the legends. Mean value histograms (B, D, F) were calculated using bin sizes of 0.04 μm²/ms for percentiles, 1 cm³ for V_ADC and 0.05 for fV_ADC. For fV_ADC mean values (F), we see that for thresholds around 1.1 μm²/ms, the mean values are reasonably evenly distributed across most of the range of the metric (0.0 to 1.0).