Skip to main content
. 2020 Jun 9;11(23):2172–2181. doi: 10.18632/oncotarget.27612

Figure 4. Landmark analysis of associations between progressive disease and weight loss percentage at landmark points (4 or 8 weeks of treatment).

Figure 4

(A) Patients were stratified according to weight loss expressed as percentage of initial weight loss during treatment. All patients who recorded any degree of weight loss/BMI decrease after 4 weeks of treatment had worse prognosis in comparison to patients who gained weight. (B) A similar tendency was observed after 8 weeks of treatment, but in this case patients who recorded a weight loss/BMI decrease of more than 3.17% from the baseline value showed worse median PFS in comparison to patients who lost less or no weight. (C) PFS Hazard ratio (HR) according to the percentage of weight loss at 4 weeks. (D) PFS Hazard ratio (HR) according to the percentage of weight loss at 8 weeks.