Figure 6.

Histology characterization of the overall HY-FIB scaffold structure with Sirius Red staining. HY-FIB scaffolds in both static and dynamic culture at Days 5 and 11 are reported; the overall scaffold structure was stained with Sirius Red for collagen highlighting. Fibrin hydrogel was light pink stained in the sample collected at Day 0. Fibrin matrix was clearly stained in red at Day 5 and 11 in both samples from static and dynamic culture. Less homogeneous scaffold matrix structure and staining was observed in samples taken from static culture.