In the article by Lip et al, “Effectiveness and Safety of Oral Anticoagulants Among Nonvalvular Atrial Fibrillation Patients: The ARISTOPHANES Study,” which was published online on November 8, 2018, and appeared in the December 2018 issue of the journal (Stroke. 2018;49:2933–2944. doi: 10.1161/STROKEAHA.118.020232), corrections are needed.
ARISTOPHANES is a pooled analysis of data from 5 US claims databases. Due to an inadvertent error with the underlying data cut received by the authors for one of the databases (the CMS Medicare database), a proportion of Medicare patients who should have been included in the analysis were excluded from the study. Specifically, those excluded patients were newly diagnosed with atrial fibrillation and initiated anticoagulation therapy in the same calendar year (2014 or 2015).
Authors have corrected the analyses by adding back those excluded patients. Results sections in the abstract and main body of the article, Table 1, Figures 1–3, Supplemental Tables II–XIII, and Supplemental Figure I have been changed to reflect the corrected analyses. These corrections have increased the sample size from 321 182 to 466 991 patients. The corrections did not result in material changes to the study findings or conclusions.
These corrections have been made to the online version of the article, which is available at https://www.ahajournals.org/doi/10.1161/STROKEAHA.118.020232.