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. 2020 Jun 12;6(6):e04160. doi: 10.1016/j.heliyon.2020.e04160

Table 3.

VentureSource keywords appearing twice or more for startups related to actively financing biopharmaceutical industry fields in 2017.

Appearance Frequency Keywords (Appearance Frequency)
Pharmaceuticals

5 or Greater drug∗' (20), 'medic∗' (12), 'cancer∗' (12), 'therap∗' (8), 'pharma∗' (8), 'health∗' (8), 'pharm∗' (8), 'nan' (7), 'pain∗' (5), 'vitamin∗' (5), 'tumor∗' (5), 'marijuana∗' (5), 'cannabis∗' (5), 'disease∗' (5), 'pharmaceutic∗' (5), 'protein∗' (5)
3–4 vaccine∗' (4), 'supplement∗' (4), 'skin∗' (4), 'oncolog∗' (4), 'antibiotic∗' (4), 'nutrition∗' (4), 'capsule∗' (4), 'intermediate∗' (4), 'biotech∗' (3), 'rare disease∗' (3), 'bacteria∗' (3), 'cardi∗' (3), 'diabetes' (3), 'plant∗' (3), 'treatment∗' (3), 'oncology∗' (3), 'therapeutic∗' (3), 'child∗' (3), 'cannabis' (3), 'medicine∗' (3), 'treat∗' (3), 'API∗' (3), 'enzyme∗' (3), 'immun∗' (3), 'blood∗' (3), 'tablet∗' (3)
2 osteo∗', 'OA', 'herpes', 'probiotic∗', 'intestin∗', 'digest∗', 'molecule∗', 'small molecul∗', 'chemother∗', 'immunoth∗', 'opioid∗', 'analges∗', 'neuro∗', 'molecul∗', 'brain∗', '∗gum∗', '∗candy∗', '∗infect∗', 'gynecolog∗', 'clinic∗', 'antimicrob∗', 'bacteri∗', 'broad-spectrum', 'cardio∗', 'develop∗', 'allerg∗', 'neurolog∗', 'cancer', 'respiratory∗', 'asthma∗', 'immune∗', 'antibod∗', 'obes∗', 'compound∗', 'antibiot∗', 'bacteria', 'super∗bug∗', 'injection∗', 'prescription', 'health', 'autoimmune∗', 'Chinese medicine', 'herb∗', 'diagnos∗', 'exosome∗', 'cosme∗', 'tissue∗', 'wrinkle∗', 'API', 'glaucoma∗', 'infect∗', 'nutraceutic∗'

Small Molecule Therapeutics

5 or Greater drug∗' (23), 'cancer∗' (22), 'therap∗' (20), 'molecule∗' (15), 'disease∗' (9), 'immun∗' (8), 'neuro∗' (8), 'health∗' (8), 'cancer' (8), 'small molecule∗' (7), 'tumor∗' (6), 'treat∗' (6), 'protein∗' (6), 'antibod∗' (6), 'cell∗' (5), 'infect∗' (5), 'molecul∗' (5), 'inflam∗' (5), 'treatment∗' (5), 'cardio∗' (5), 'small molecule' (5), 'oncolog∗' (5)
3–4 therapeutic∗' (4), 'medic∗' (4), 'pathogen∗' (4), 'chronic∗' (4), 'Alzheimer∗' (4), 'biotech∗' (3), 'immuno∗' (3), 'food' (3), 'ion channel' (3), 'inhibit∗' (3), 'nano∗' (3), 'immune∗' (3), 'C5a′ (3), 'terminal∗' (3), '∗infect∗' (3), 'therapeut∗' (3), 'bio∗' (3), 'kinase∗' (3), 'tumor' (3), '∗onco∗' (3), 'diagnos∗' (3), 'PSVT' (3), 'calcium∗' (3), '∗ventricul∗' (3), 'brain∗' (3), 'neurodegenerat∗' (3)
2 biopharma∗', 'affinity purification', 'bioprocess∗', 'onco∗', 'AI', 'substitut∗', 'plant∗', 'milk', 'cheese∗', 'mayonnaise∗', 'yogurt∗', 'emul∗', 'mitochondrial', 'eosinophil', 'leukocyte', '∗immun∗', 'skin∗', 'spray∗', 'resist∗', 'bacteria∗', 'antibiotic', 'AF', 'heart∗', 'peptide∗', '∗cell∗', 'derma∗', 'nerv∗', 'molecule', 'oncolo∗', 'rare disease∗', 'ossific∗', 'fibrodysplasia', ' (RAR)', 'integrin', 'antibiotic∗', 'breast∗', '∗cancer', 'treatment', 'neurolog∗', 'protein', 'lung', 'apoptosis', 'respiratory∗', 'therapeutic', '∗cancer∗', 'fibrosis', 'GSK-3ß′, 'Glycogen Synthase Kinase', 'bipolar disorder', 'diabetes'

Biotechnology Therapeutics

5 or Greater cancer∗' (28), 'therap∗' (20), 'drug∗' (16), 'disease∗' (12), 'biotech∗' (11), 'cell∗' (9), 'health∗' (8), 'diseas∗' (7), 'disorder∗' (7), 'diagnos∗' (7), 'gene∗' (7), 'tumor∗' (7), 'medic∗' (6), 'bacteria∗' (6), 'neuro∗' (6), 'DNA' (6), 'oncolog∗' (6), 'Alzheimer∗' (5), 'cleantech' (5), 'treat∗' (5), 'cancer' (5), 'tissue∗' (5)
3–4 molecule∗' (4), 'immune∗' (4), 'therapeut∗' (4), 'antibod∗' (4), 'therapeutic∗' (4), 'industry focused products and services' (4), 'infect∗' (4), 'regenerat∗' (4), 'protein∗' (4), 'microbiome' (4), 'treatment∗' (4), 'immun∗' (4), 'neurolog∗' (3), 'Alzheimer's∗' (3), 'spinal cord∗' (3), 'injur∗' (3), '∗amyloid∗' (3), 'receptor' (3), 'central nervous system∗' (3), 'CNS' (3), 'antibiotic∗' (3), 'compound∗' (3), 'onco∗' (3), 'CMBC' (3), 'pharma∗' (3), 'skin∗' (3), 'molecule' (3), 'vaccine∗' (3), 'inhibitor∗' (3), 'inflam∗' (3), 'respirat∗' (3), '∗cancer∗' (3), 'bone∗' (3), 'pharm∗' (3)
2 blood∗', 'platelet∗', 'manufact∗', 'contract∗', 'life scienc∗,', 'metaboli∗', 'inflammat∗', 'microbe∗', 'inhal∗', 'cardiovascular', 'PAF', 'biotech∗ atria∗', 'arrhythmia', 'paediatr∗', 'nephrolog∗', 'renal∗', 'neurologic∗', 'orphan∗', 'anaesthes∗', 'tubulo∗', 'oil', 'protein', 'insect∗', 'agriculture', 'lysom∗', 'stor∗', 'HSP', 'misfold∗', 'degenerat∗', 'hear∗', 'cochlear∗', 'ear∗', 'noise', 'restor∗', 'cardiovascular∗', 'myelofibrosis', 'MF', 'JAK2′, 'ocular∗', 'probiotic∗', 'research∗', 'clinical trial∗', 'osteoporos∗', 'hypoparathy∗', 'hypoparathyroidism∗', 'biopharm∗', 'drug discover∗', 'genomic∗', '∗microbiome∗', 'th + F5eepeutic∗', 'urea cycle disorder∗', 'pathogenic∗', '∗bacteria∗', '∗health∗', 'fish∗', '∗inflamation + F23∗', 'detect∗', 'vir∗', 'T-cell∗', '∗immune∗', 'dermatolog∗', 'aesthetics', 'plasmotic', 'acne', 'hair removal', 'topical', 'vascular', 'COPD', 'addict∗', 'opiate∗', 'alcohol', 'abuse∗', 'silk∗', 'aesthetic∗', 'defect∗', 'diabetes', 'obes∗', 'molecular∗', 'rare disease∗', '∗skelet∗', 'drug', 'molecul∗', 'metabolic', 'intestin∗', 'antibody'

Gene Therapy

5 or Greater gene∗' (29), 'therap∗' (19), 'cancer∗' (16), 'DNA' (10), 'drug∗' (7), 'genomic∗' (5), 'cancer' (5), 'health∗' (5), 'oncolog∗' (5), 'cell∗' (5)
3–4 DNA∗' (4), 'genom∗' (4), 'patient∗' (4), 'immun∗' (4), 'CRISPR' (4), 'gene therap∗' (4), 'cure' (4), 'therapy' (4), 'gen∗' (4), 'disease∗' (4), 'biotech∗' (4), 'virus' (3), 'gene' (3), 'AAV' (3), 'virus∗' (3), 'diseas∗' (3), 'immune∗' (3), 'brain' (3)
2 Parkinson∗', 'DTC genetic test∗', 'therapeutics∗', 'genetic research∗', 'medic∗', 'adeno∗', 'treat∗', 'Cas9′, 'duchenne', 'dystroph∗', '8muscular disease∗', 'viral∗', 'tumor∗', 'research∗', 'animal∗', 'livestock', 'agricultur∗', 'breed∗', '∗medic∗', 'retina∗', 'dystrop∗', 'choroid∗', 'degenerat∗', 'CHM', 'REP-1′, 'protein∗', 'rare disorder∗', 'treatment∗', 'adeno', 'medical', 'treatment', 'health', 'stem cell∗', 'CAR-T′, 'HIV', '∗gene∗', 'chimer∗', 'receptor∗', '∗cell∗', 'CAR', 'life scien∗', 'genetic engineer∗', 'personal∗ medic∗', 'molec∗ bio∗', 'HCP', 'cell protein', 'genome∗', 'glioblastoma'

Immunotherapy/Vaccines

5 or Greater 'cancer∗' (31), 'immun∗' (22), 'tumor∗' (15), 'therap∗' (14), 'antibod∗' (13), 'disease∗' (13), 'vaccine∗' (12), 'infect∗' (12), 'cancer' (11), 'drug∗' (11), 'vaccin∗' (10), 'virus∗' (8), '∗immun∗' (8), 'antigen∗' (7), 'T cell∗' (6), 'cell∗' (6), '∗therap∗' (5), 'protein∗' (5)
3–4 'oncolog∗' (4), 'allerg∗' (4), '∗cancer∗' (4), 'immuno∗' (4), 'disease' (3), 'biotech∗' (3), 'inflammat∗' (3), 'viral∗' (3), '∗tumor∗' (3), 'antibody∗' (3), 'ADC' (3), 'medicine∗' (3), 'ag∗' (3), 'immunosenescence' (3), '∗infect∗' (3), 'antibiotic∗' (3), 'inflam∗' (3), 'medic∗' (3), 'prevent∗' (3), 'RSV' (3), 'target∗' (3), 'T-cell' (3)
2 'therapeutic∗', 'oncology', 'RNA', 'DNA', 'HIV', 'TME', 'patient', 'pathogen∗', 'bacteria∗', 'monoclonal', 'complement system', 'COPD', 'AMD', 'PNH', 'virus', 'treatment', 'patho∗', '∗oncolog∗', 'respirat∗', 'licens∗', 'rhinovirus', 'cold∗', 'asthma∗', '∗vir∗', 'mosquito∗', 'Zika', 'Dengue∗', '∗fever∗', 'Hepati∗', 'nanomedicine∗', 'colorectal∗', 'purif∗', 'oncol∗', 'viral', 'dendritic', 'biopharma∗', 'diseas∗', 'oncobio∗', 'microb∗', 'tumor', 'antigen'