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. 2020 Jun 12;6(6):e04160. doi: 10.1016/j.heliyon.2020.e04160

Table 4.

Keyword frequency growth multiple in web of science core collection related to active financing in biopharmaceutical industry fields during 2014–2017.

Rank Keyword Start Year Count End Year Count Growth (×)
Pharmaceuticals

1 therap 1 6 6.00
2 cardi 2 7 3.50
3 super∗bug 9 29 3.22
4 exosome 400 880 2.20
5 cosme 4 8 2.00
6 immun 7 14 2.00
7 allerg 1 2 2.00
8 antibod 1 2 2.00
9 obes 23 44 1.91
10 marijuana 993 1431 1.44

Small Molecule Therapeutics

1 therap 1 6 6.00
2 inflam 1 3 3.00
3 immun 7 14 2.00
4 ventricul 1 2 2.00
5 PSVT 9 14 1.56
6 mayonnaise 41 60 1.46
7 yogurt 396 576 1.45
8 ossific 7 10 1.43
9 onco 126 178 1.41
10 rare disease 8249 11429 1.39

Biotechnology Therapeutics

1 therap 1 6 6.00
2 inflam 1 3 3.00
3 microbiome 1732 4403 2.54
4 immun 7 14 2.00
5 injur 1 2 2.00
6 inflammat 1 2 2.00
7 diseas 4 8 2.00
8 obes 23 44 1.91
9 restor 23 35 1.52
10 paediatr 8 12 1.50

Gene Therapy

1 therap 1 6 6.00
2 Cas9 448 2384 5.32
3 CAR-T 97 485 5.00
4 CRISPR 694 3138 4.52
5 DTC genetic test 13 29 2.23
6 immun 7 14 2.00
7 diseas 4 8 2.00
8 CHM 104 152 1.46
9 AAV 566 813 1.44
10 molec∗ bio 1335 1829 1.37

Immunotherapy/Vaccines

1 Zika 26 2310 88.85
2 therap 1 6 6.00
3 inflam 1 3 3.00
4 allerg 1 2 2.00
5 immun 7 14 2.00
6 antibod 1 2 2.00
7 diseas 4 8 2.00
8 inflammat 1 2 2.00
9 TME 192 365 1.90
10 Dengue 1775 2729 1.54