1.
Martín Carreras‐Presas, Amaro Sánchez, López‐Sánchez, Jané‐Salas, and Somacarrera Pérez (2020) reported three cases in May in Oral Diseases that they suggested was the first case report describing of a COVID‐19 patient with oral manifestations including oral pain, desquamative gingivitis, ulcers, and blisters. Galván Casas et al. (2020) provided a description in April in the British Journal of Dermatology of the cutaneous manifestations of COVID‐19 in an impressive 375 case series, and with that, they had documented for the first time the oral manifestations of the disease. The report includes an atlas of these manifestations as a downloadable supplement that includes apparently 150 different cases and among those, three cases with intra‐oral manifestations that vary from ulcers in the palatal mucosa, to localized erythema in the palate and the margins of gingiva.
It is not surprising COVID‐19 has oral manifestations, since many other viral infections also have similar presentations (Clarkson, Mashkoor, & Abdulateef, 2017; Nedwick‐Castro & Vieira, 2012). It will be interesting to determine in the near future how frequent those manifestations are in individuals presenting symptoms in contrast to infected asymptomatic. We evaluated a 32‐year‐old White male that had shortness of breath associated with coughing for one‐week early March and three weeks later developed pseudo‐chilblain. He keeps good oral hygiene and had no prior signs of gingival inflammation, and although reporting higher levels of stress and less rigorous oral hygiene during the episode, he did not show any signs of gingival bleeding or inflammation. Therefore, we hypothesize that mild cases of COVID‐19 may not show any oral manifestations. For the severe cases, in which a persistent inflammatory status appears to act as a trigger for the coagulation cascade and is associated with increased levels of fibrinogen degradation products (e.g., D‐dimer) (Cao & Li, 2020), we believe that prior underlying untreated moderate or severe periodontitis may worsen COVID‐19. Conversely, periodontal therapy in individuals with initial COVID‐19 symptoms may reduce the risk of the condition to become severe by reducing the amount of D‐dimer in the plasma, which is what we see when patients with periodontitis are treated (Dikshit, 2015).
CONFLICT OF INTEREST
The author has no conflict of interest to report.
AUTHOR CONTRIBUTION
Alexandre Vieira: Conceptualization; Data curation; Formal analysis; Funding acquisition; Investigation; Methodology; Project administration; Resources; Writing‐original draft.
REFERENCES
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ACKNOWLEDGEMENTS
There are no sources of funding to report. The author contributed to conception, design, data acquisition, and interpretation, drafted and critically revised the manuscript.