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. 2020 Jun 19;12(6):e8693. doi: 10.7759/cureus.8693

Table 2. Immunophenotypic characteristics of MM, pPCL, and sPCL.

MM: multiple myeloma; pPCL: primary plasma cell leukemia; sPCL: secondary plasma cell leukemia; IgH: immunoglobulin heavy chain; HLA: human leukocyte antigen; NCAM: neural cell adhesion molecule; LFA-1: leukocyte function-associated antigen 1

Features of MM, pPCL, and sPCL Features of pPCL AND sPCL Features of pPCL Features of sPCL
Presence of CD38, CD 138 CD 2, CD 3, CD 10, CD 13 CD 15, CD 16 Presence of CD 20, CD 23, CD 44, CD 45, IgH translocations, MYC translocations/amplifications, 17 p deletion, 1p21 deletion, 1q21 amplification; lack of CD 9, CD 56, CD 71, CD 117, HLA DR, NCAM, LFA-1 Presence of t(11;14) Presence of CD 28, t(4;14), t(14;16)