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. 2020 Jun 5:taaa094. doi: 10.1093/jtm/taaa094
Exposure to SARS-CoV-2 in a high transmission setting increases the risk of severe COVID-19 compared to exposure to a low transmission setting?
Dong Chen
1,#, Chenchan Hu
1,#, Feifei Su
1,#, Qifa Song
3, Zhen Wang
2,✉
Dong Chen, MD
1
Departments of Infectious Disease, The Ding Li Clinical College of Wenzhou Medical University and Sixth People’s Hospital of Wenzhou, Wenzhou, Zhejiang, China
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Chenchan Hu, BS
1
Departments of Infectious Disease, The Ding Li Clinical College of Wenzhou Medical University and Sixth People’s Hospital of Wenzhou, Wenzhou, Zhejiang, China
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Feifei Su, BS
1
Departments of Infectious Disease, The Ding Li Clinical College of Wenzhou Medical University and Sixth People’s Hospital of Wenzhou, Wenzhou, Zhejiang, China
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Qifa Song, MSc
3
Central Laboratory, Ningbo First Hospital, Ningbo, Zhejiang Province, China
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Zhen Wang, Ph.D
2
Research Center of Blood Transfusion Medicine, Ministry of Education Key Laboratory of Laboratory Medicine, Zhejiang Provincial People’s Hospital, People’s Hospital of Hangzhou Medical College, Hangzhou, China
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1
Departments of Infectious Disease, The Ding Li Clinical College of Wenzhou Medical University and Sixth People’s Hospital of Wenzhou, Wenzhou, Zhejiang, China
2
Research Center of Blood Transfusion Medicine, Ministry of Education Key Laboratory of Laboratory Medicine, Zhejiang Provincial People’s Hospital, People’s Hospital of Hangzhou Medical College, Hangzhou, China
3
Central Laboratory, Ningbo First Hospital, Ningbo, Zhejiang Province, China
✉
To whom correspondence should be addressed. wangzhen@hmc.edu.cn
#
Dong Chen, Chenchan Hu and Feifei Su contributed equally to the article. All authors read and approved the final manuscript.
Received 2020 Apr 18; Revised 2020 May 9; Accepted 2020 May 29.
Keywords: Coronavirus Disease 2019 (COVID-19), Epicentre, Severity of disease, Repeat exposure, Viral load, Case fatality rate, Health-care resource availability
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PMCID: PMC7313864 PMID: 32502262