Figure 2. Comparison of exon/intron structure of genes encoding precursors of PrRP-like peptides in echinoderms and hemichordates with precursors of PrRP-type peptides in chordates.
Schematic representations of the gene structures are shown, with protein-coding exons shown as rectangles and introns shown as lines (with intron length stated underneath). The protein-coding exons are colour-coded to show regions that encode the N-terminal signal peptide (blue), the neuropeptide (red), monobasic or dibasic cleavage sites (green) and other regions of the precursor protein (grey). Note that a common characteristic is that an intron interrupts the coding sequence in the N-terminal or central region of the neuropeptide, with the intron consistently located between the first and second nucleotides (phase one intron represented by +1) of the codon for the amino acid shown after intron. Taxa are highlighted in phylum-specific colours: dark blue (Echinodermata), light blue (Hemichordata), purple (Chordata). The full names of the species and the accession numbers of the sequences are listed in Figure 2—source data 1.
Figure 2—figure supplement 1. Comparison of the exon/intron structure of genes encoding echinoderm precursors of PrRP-like peptides and genes encoding NPY/NPF-type precursors in other taxa.
