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. 2020 Jun 23;11(3):e01293-20. doi: 10.1128/mBio.01293-20

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FIG 3 — CD47 is involved in innate licensing of adaptive immune responses in HCV patient clinical samples. (A) Comparison of CD47 expression from Affymetrix array profiles of liver biopsy specimens from two healthy controls and six patients with acute HCV infection (P = 0.03 by an unpaired two-way t test) (NCBI GEO accession number GSE38597). (B and C) Comparison of CD47 expression by CyTOF MFI on CD14⁺ monocytes (B) and HLA-DR⁺ DC subpopulations (C) isolated from HCV-infected sofosbuvir-treated patients before the initiation of treatment (Pre), midway through treatment (Mid), and after treatment (Post) compared to healthy controls. (D) Comparison of CD47 expression on SIRPα^lo versus SIRPα^hi DCs from healthy control and HCV patients. Statistics were done by one-way ANOVA with multiple-comparison posttests (ns, P > 0.05; *, P < 0.05; **, P < 0.01). Error bars represent SEM.