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. Author manuscript; available in PMC: 2021 Sep 1.
Published in final edited form as: Neuropharmacology. 2020 May 23;174:108159. doi: 10.1016/j.neuropharm.2020.108159

Figure 3. Activation of group III mGluRs reduces glutamate release to spinally projecting PVN neurons in WKY rats and SHRs.

Figure 3.

A, Original recordings show that L-AP4 decreased the frequency of sEPSCs in labeled PVN neurons in a concentration-dependent manner in WKY rats and SHRs. B-E, Cumulative probability analyses show that L-AP4 decreased the frequency (D and E), but not the amplitude (B and C), of sEPSCs in labeled PVN neurons in WKY rats and SHRs. F and G: Summary data show the effect of L-AP4 on the frequency (F) and amplitude (G) of sEPSCs in labeled PVN neurons in WKY rats (n = 13 neurons from 4 rats) and SHRs (n = 15 neurons from 4 rats). *P < 0.05 and **P < 0.01, compared with the baseline for the group. ##P < 0.01, compared with the baseline in WKY rats.