Fig. 4.

CD4⁺ T cell susceptibility to HIV and viral inhibition by CD8⁺ T and NK cells.

PBMC samples before initiation of cART and after 5 years on cART were used to analyse the susceptibility of CD4⁺ T cells to HIV BaL (CCR5 tropic strain) (10 ng p24/ml) (a). We also measured the ex vivo ability of CD8⁺ T cells (b) and NK cells (c) to inhibit superinfected autologous CD4⁺ T cells at a 1:1 ratio. The cp-LoViReT group is depicted in blue and the control group in grey.