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. 2020 Feb 8;68(7):1445–1465. doi: 10.1002/glia.23792

Figure 7.

Figure 7

Absence of Mmp‐9 results in an altered inflammatory response following photoreceptor death. Time‐course of the expression of inflammatory genes, tnf‐β (a; ANOVA F‐ratio = 19.2406, p < .0001,), nfκβ1 (b; ANOVA F‐ratio = 10.4104, p < .0001), nfκβ2 (c; ANOVA F‐ratio = 10.4104, p < .0001), il‐8 (d; ANOVA F‐ratio = 185.42, p < .0001), and tnf‐α (e; ANOVA F‐ratio = 54.53, p < .0001) in Wild‐type (black bars) and Mmp‐9 mutant (gray bars) retinas following photoreceptor death. Fold changes relative to unlesioned retinas of Wild‐type are calculated using DDCt method. ANOVA with post‐hoc Tukey, *p < .0001