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. 2020 May 27;25(11):2498. doi: 10.3390/molecules25112498

Table 6.

TER marker bands of the neurodegenerative peptide aggregation.

Marker Band of the Aggregation [cm−1] Assignment Peptide Reference
amide I (1700–1600 cm−1)
1680–1660 ↑ β-sheets amyloid β1-42, insulin, [111,113,115,116,117,118]
β2-microglobulin
1674 ↑ β-sheets hIAPP (Amylin) [112]
1655–1630↓ random coil amyloid β1-42 [117]
1640↓,1664–1640 ↓ α-helics, unordered hIAPP (amylin), insulin [112,113,115,118]
Cα H/N-H (1370–1360 cm−1)
1364 ↑ β-sheets amyloid β1-42 [116]
amide III (1283–1218 cm−1)
1228–1218 ↑ parallel β-sheets amyloid β1-42 [117]
1242–1233, 1250↑ antiparallel β-sheets insulin [116,117]
1235–1230↑ β-sheets amyloid β1-42, [111,115]
1261–1248, 1258 ↓ random coil β2-microglobulin [116,117]

↓ a decrease of peak intensity with the ongoing fibrillation, ↑ an increase of peak intensity with the ongoing fibrillation.