Table 6.
Marker Band of the Aggregation [cm−1] | Assignment | Peptide | Reference |
---|---|---|---|
amide I (1700–1600 cm−1) | |||
1680–1660 ↑ | β-sheets | amyloid β1-42, insulin, | [111,113,115,116,117,118] |
β2-microglobulin | |||
1674 ↑ | β-sheets | hIAPP (Amylin) | [112] |
1655–1630↓ | random coil | amyloid β1-42 | [117] |
1640↓,1664–1640 ↓ | α-helics, unordered | hIAPP (amylin), insulin | [112,113,115,118] |
Cα H/N-H (1370–1360 cm−1) | |||
1364 ↑ | β-sheets | amyloid β1-42 | [116] |
amide III (1283–1218 cm−1) | |||
1228–1218 ↑ | parallel β-sheets | amyloid β1-42 | [117] |
1242–1233, 1250↑ | antiparallel β-sheets | insulin | [116,117] |
1235–1230↑ | β-sheets | amyloid β1-42, | [111,115] |
1261–1248, 1258 ↓ | random coil | β2-microglobulin | [116,117] |
↓ a decrease of peak intensity with the ongoing fibrillation, ↑ an increase of peak intensity with the ongoing fibrillation.