Figure 4.

Validation of the drug combinations in non-cancerous cell lines. Validation of the clinically used dose (CUD) combination and each of the cell-specific ODCs at low doses in various non-cancerous cell lines presented with drug combination efficacy on cell metabolic activity. Error bars represent the SD for N = 2–3 experiments and significances of * p < 0.05, ** p < 0.01 and *** p < 0.001 represent the comparison with the CUD combination for all cell lines by a one-way ANOVA with post-hoc Dunnett’s multiple comparisons test.