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BPTES reduces Col I protein. (A) BPTES treatment significantly decreases the Col I protein production in iLTS scar fibroblasts compared to untreated fibroblasts at 24 hours. DMK successfully rescues the Col I protein production in BPTES-treated fibroblasts. *P < .05. (B) Col I protein expression is reported on a per-subject basis. BPTES = bis-2-(5-phenylacetamido-1,3,4-thiadiazol-2-yl) ethyl sulfide; Col I = collagen 1; DMK = dimethyl 2-oxoglutarate.
