Table 2.

Input parameters for RSV disease burden in children.

Parameter	UA	PATH	Source
Annual incidence of RSV-ALRI per 1,000 children under 5	Country-specific estimates (35.3 to 65.6)	Country-specific estimates (35.3 to 65.6)	[7, Supplementary Table 18*]
Annual incidence of RSV-ALRI per 1,000 children under 5, by age group	Developing country estimate	Developing country estimate	[7, supplementary Table 9*]
0–27 days	40.0	40.0
28–< 3 months	45.7	45.7
3–5 months	99.6	99.6
6–11 months	98.8	98.8
12–23 months	79.1	79.1
Annual incidence of severe RSV-ALRI per 1,000 children under 5, by age group	Not included due to insufficient age-specific data	Developing country estimate	[7, Table 1*]
0–5 months	NA	36.1
6–11 months	NA	24.7
0–59 months	NA	10.2
Annual hospital admissions for RSV-associated ALRI per 1,000 children under 5, by age group	Developing country estimate	Developing country estimate	[7, Supplementary Table 20 for UA estimate, and Table 1 for PATH estimate*]
0–5 months	0–27 days: 15.9; 28 days–3 months: 26.1; 3–5 months: 20.7	20.2
6–11 months	6–8 months: 12; 9–11 months: 11.3	11
Hospital case fatality risk (%), by age group	Developing country estimate	Developing country estimate	[7, Supplementary Table 20 for UA estimate, and Table 2 for PATH estimate*]
0–5 months	0–27 days: 5.3; 28 days–3 months: 2.3; 3–5 months: 2.4	2.2
6–11 months	6–8 months: 3.0; 9–11 months: 3.6	2.4
Disability weight for DALY calculation			[18]
Severe ALRI	0.21	0.21
Non-severe ALRI	0.053	0.053
Duration of illness (days)	11.2	11.2	[19]

Abbreviations: ALRI, acute lower respiratory infection; DALY, disability-adjusted life year; NA, not applicable; RSV, respiratory syncytial virus; UA, University of Antwerp in partnership with the London School of Hygiene & Tropical Medicine. Table numbers represent tables from the source literature [7] from where the input values were derived.