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PLOS One logoLink to PLOS One
. 2020 Jul 9;15(7):e0235068. doi: 10.1371/journal.pone.0235068

Keeping the power on to home medical devices

Richard Bean 1,*, Stephen Snow 1, Mashhuda Glencross 1, Stephen Viller 1, Neil Horrocks 1
Editor: Talib Al-Ameri2
PMCID: PMC7347141  PMID: 32645015

Abstract

Advances in digital health technologies have revolutionised home medical care. Yet many home medical devices (HMEDs, which includes devices referred to as ‘life support equipment’) rely upon a stable and resilient electricity supply. For users of HMEDs, interruptions to electricity supply can compromise treatment, well-being or survival. This paper addresses a challenge critical to the continued innovation in digital health technologies: the reliable supply of electricity. We bridge the current gap between electricity networks and digital health technologies through a novel method for the remote detection of the phase (that is, which part of the network that each house is connected to), in order to eliminate avoidable interruptions to supply for HMED users. We present an unsupervised phase identification algorithm capable of remote phase detection at scale, and without transformer data. This method translates data insights into actionable energy provision for HMED users and other vulnerable customers, enables more accurate management and planning, and improves electricity reliability which is critical for HMED users and the continued advances in digital health technologies.

Introduction

Advances in digital health technologies are revolutionising healthcare. The total global market for mHealth was calculated in 2015 to be worth $21.5 billion [1]. A key impact of the proliferation of remote and mHealth care is the number of people being able to access hospital treatment at home. Electricity is fundamental to the basic function and advancement of digital health technologies (DHT), powering home medical devices (e.g. machines for dialysis, physiotherapy, oxygen delivery or CPAP machines), enabling tele-medicine, and charging devices with batteries. Yet discussions of electricity and access to electricity are largely absent from academic discourse on DHTs to date, given the relative ubiquity and stability of supply of electricity in developed countries. However, the consequences of a disruption to supply for those reliant on certain DHTs can be harmful or even fatal [2, 3].

In the design of DHT where batteries are involved, (e.g. wearables, smart phone apps, mobility aids), power consumption may commonly be considered within the context of extending battery life and minimising the need for frequent charging [4]. Yet contingencies or preparedness for the loss of ability to charge, or the function of DHTs in the absence of access to electricity is rarely considered outside of situations in which DHTs are designed specifically for environments in which data (WIFI/3G) is lacking (e.g. remote locations or developing world contexts [5]).

Most other DHTs rely on continuous power supply. A recent US study identified over 685, 000 electricity dependent users who reside at home [2]. Electricity dependence is defined by vulnerable populations “… who depend on durable medical equipment (DMEs) that are electrically powered” [2]. This includes those reliant on electricity for independence, (e.g. electric wheel-chairs, mobility scooters etc), as well as those reliant on electricity for survival, (e.g. those with ventilators, oxygen concentrators, reliance on exceptional temperature stability or other critical at-home medical devices). A much larger subset of the population may additionally be considered electricity vulnerable, such as those susceptible to heat/cold, or with limited mobility to leave home in a blackout [6].

Existing meta reviews of digital health technologies focus on communications [7], patient and family factors in implementation [8]and reporting quality [9]. Yet despite being fundamental to the majority of DHTs, stable electricity supply or contingency for loss of supply remains a knowledge gap.

With advances in DHT technology, tele-medicine, in-home medical devices, and support for independent living, enabling more people to remain in-home for longer, the number of electricity dependent and electricity vulnerable people is projected to increase significantly in coming years [2, 3]. Given the scientific consensus that climate change is likely to cause an increase in extreme weather events [10], increased intensity of hurricanes, prevalence of extreme heat and extreme cold events, and increased severity of flooding [11], it can also be extrapolated that weather-related disruptions to electricity supply will become more prevalent in the years ahead. Already, large-scale blackouts and extreme weather events result in significant spikes in emergency hospital admissions from those losing operation of in-home medical devices [1214]. The advancement of DHT as a research agenda, is therefore dependent on its ability to withstand interruptions to the electricity supply upon which many DHTs rely; underscoring the salience of research which bridges the current research gap between DHT design, energy network management and disaster response.

This paper represents the foundations for these bridges, arguing for a need to factor emergency preparedness into DHT design. We describe the design and testing of a method for minimising the risk of network operators accidentally disconnecting customers with home medical devices. Through the use of a novel data-driven machine learning approach, we detect the phase connection to domestic homes, enabling network operators to verify if a HMED user is connected to a phase that might be interrupted and action a suitable response to mitigate potential harm. We report on the performance testing of this algorithm before discussing (1) the need for closer collaborations between designers of medical devices, energy network operators and health policy makers, and (2) further potential values of detailed energy usage information required for this algorithm for vulnerable energy users and at-home medical device operators.

Background

Digital Health Technology (DHT) affords a growing ability for medical patients to receive care at home. In 2004 it was estimated that over seven million US residents received home health care annually, many of which involved the use (or continuing use) of in-home medical devices [15, 16]. Yet the guidance available to users for power outage for in-home medical devices is limited. With regard to electricity supply, “Design Considerations for Devices Intended for Home Use”, aimed at manufacturers of home-medical devices states only that designers and manufacturers might “… consider providing or identifying backup power options, such as a battery or generator”, and instructions on the device labelling for emergency contact information in the event of an outage [16].

Treating electrical emergencies

While hospitals and other critical infrastructure are typically fitted with onsite backup generation for use during blackouts, multiple studies have demonstrated the substantial effect of power disruptions on people with home medical devices. Rubin and Rogers [17] highlight how hospitals in Louisiana following Hurricane Isaac in 2012 were essentially treating “electricity emergencies” rather than medical emergencies; namely people who could no longer operate electricity dependent medical or enabling devices. Libraries and shelters set up by charities acted as “electricity shelters”, reducing the burden on hospitals. People with home medical devices accounted for 22% of all hospital admissions in a 24 hour period following the 2003 New York blackouts [13]. Due to the “en-masse” movement of home medical device patients to local hospitals following the 2011 Japan earthquake, authors conclude such events have the potential to “overwhelm the capacity of hospital inpatient facilities” [12]. Even planned load shedding events in South Africa have been correlated (with causation established) to a 10% increase in hospital admissions, including from medical device patients and those with secondary effects, including carbon monoxide poisoning from petrol generators and food poisoning from lack of refrigeration [18].

In response, authors argue for the need for vulnerability assessments of power grids, understanding the likely nature of blackouts both physically (i.e. which areas will lose power first/last) and socially (i.e. what are the demographics of these areas, where are registered medical device users located) [19].

Existing preparedness: The Australian network context

In Australia, the retail electricity environment is governed by the National Electricity Retail Rules (NERR) and the National Electricity Retail Law (NERL) [20]. Published in February 2019, the NERL has specific provision for the conduct of energy service providers (e.g. network operators) around life support equipment. The Law defines life support equipment as one of the following:

  • an oxygen concentrator

  • an intermittent peritoneal dialysis machine

  • a kidney dialysis machine

  • a chronic positive airways pressure respirator

  • Crigler-Najjar syndrome phototherapy equipment

  • a ventilator for life support

  • any other equipment that a registered medical practitioner certifies is required for a person residing at the customer’s premises for life support

Users with HMEDs can apply for recognition as a life support customer with their electricity retailer or network operator. Yet it is unlikely that these records provide a complete picture of electricity dependent users. This is due to: (1) it is unlikely that 100% of home medical equipment users will have identified themselves to their retailer or the network, and (2) people with short term (e.g. two to three day) loans of medical equipment may be unlikely to bother applying, relative to continual users.

The NERR include the requirement for electricity retailers and network operators to not arrange for de-energisation of the premises associated with a registered life support customer unless they provide advanced notification of planned outages. While weather events, natural disasters and their impact on a network reliability cannot currently be predicted, The Australian Energy Regulator (AER) issues substantial infringement notices for failing to notify electricity dependent customers of planned interruptions of supply. A company may be fined $20,000 (as of 2020) if the company fails to provide at least four business days written notice of a planned interruption to electricity supply [21].

A common cause of accidental disconnection or failure to notify customers is inaccurate records regarding the point at which the customer is connected to the network. Residential power supply in Australia consists of three low voltage electrical conductors (called phases) and customers can be connected to any of these phases. Some households are connected to power poles where two separate power supplies, fed from two entirely different sources, may terminate. In these instances, a household could feasibly be connected to any one of six phases.

Depending on the age of a suburb, the initial allocation of houses to phases can predate computer records by many decades, depending on when the house was constructed. The initial record may have been transmitted from paper to computer records, and further between each generation of computer record (magnetic tape, magnetic drive, solid state, and cloud storage). Transmission errors and errors in recording phases occur frequently and the network operator is sometimes unaware of the actual accuracy of their records. Further, whenever an extreme weather event occurs, houses may be reallocated to different phases in the heat of a crisis. Hence while it is in a utility’s best interests to have a completely accurate record of the phase allocation of each house attached to a feeder / transformer, in reality this is rarely possible. The issue of inaccurate connection point data is not unique to Australia, with utilities across the world reporting similar problems [22].

To summarise: (1) power outages cause life threatening situations for electricity dependent populations and “electricity emergencies” can stretch the capacity of local hospitals and medical centres. (2) Despite efforts to identify electricity dependent individuals for emergency preparedness, achieving 100% coverage is highly unlikely, due to some users failing to register. (3) Network data on which houses are connected to which phases is imperfect, increasing the chance that even registered users of HMEDs may be adversely impacted by planned outages and natural disasters. (4) These issues are generalisable globally [22].

In order to address this problem, we provide a proof of concept for a phase detection algorithm which holds potential for substantially reducing the impact of power disruptions to HMED users.

Proof of concept: Remote phase detection

Ordinarily, to manually check the phase of all the houses on a transformer (there are approximately 100 houses connected to each transformer in urban areas), takes a team of technicians several hours. Hence the ability to carry out this work remotely using data analysis techniques is valuable in both time and money, and minimises the chance of disruption of supply to HMED users. As the benefits of big data analytics become more apparent to network operators they will install more and better power sensing technology at customer premises (including smart meters and IoT power quality devices). It is these new sensors that offer the ability to provide real time information on connection point detail and updates on in-field changes.

Measurement device

Remote phase detection requires behind-the-meter data capture of voltage, current and impedance at regular intervals of at least one minute. Devices capable of this frequency of data capture include: smart meters, which transmit energy use information to the utility at five to 60 minute increments [23]; home energy monitoring sensors; sensors installed in WIFI-enabled rooftop solar inverters and home battery storage; or custom built sensors, which can provide sub-minute granularity. While smart meters are being rolled out across Europe with many countries now at > 80% saturation [24], smart meter saturation is far lower in Australia, and behind-the-meter sensors capable of sub-minute data capture offer opportunities for phase detection (amongst other benefits). The Redback Technologies Ouija Lite (used in this study) is one such low-cost sensor which captures voltage, current, impedance and power factor data at each house it is connected at one minute resolution. It transmits this data to a cloud service through the use of Sigfox devices (or other 4G telecommunication network devices).

The infrastructure can be represented as in Fig 1.

Fig 1. Cloud infrastructure.

Fig 1

The Power Analyzer device is attached to the house. It measures the energy data at two points Grid and Generation data) and passes it to the Ouija Lite device. This device then transmits data packets, once per minute, via Sigfox, to Microsoft Azure storage in the cloud. Using a Shared Access Key, the cloud storage data can be downloaded and processed using routines in, for example, the R or Python programming languages.

Generally each transformer in a residential area has three active LV (low voltage) phases connected and each house is then connected to one of these three phases. Electricity network operators balance the number of houses connected to each phase.

Clustering methods

Remote phase detection algorithms are in their infancy and few examples from peer-reviewed literature exist. Pezeshki and Wolfs [25, 26] proposed a supervised clustering method using correlation to identify the phases of houses in an LV network in Perth, Western Australia. They looked at 51 single phase houses and 24 three phase houses. Voltage data from the houses was collected from the smart meters in each house (15 minute periods). This is the minimum resolution at which consumer smart meters record this data.

In order for this correlation based method to work, transformer level voltage data is also required. At the transformer, the average voltage over the same time period was calculated. For each house, the phase with the highest correlation was chosen as the putative phase for that house. This resulted in a correct allocation of phases for each house.

In other work, Wang et al [27] looked at a constrained k-means clustering algorithm to analyse a network in Southern California while Wang et al [22] applied a constraint-driven hybrid clustering algorithm, and Blakely et al [28] used spectral clustering.

Our method

We propose a new algorithm for identifying phases in a group of houses connected to a transformer. The new algorithm is unsupervised and does not require access to transformer level voltage data, as the supervised approach of Pezeshki and Wolf [25, 26] does. Instead, voltage time series data is collected at each of the houses for the purpose of the analysis.

We assess the stability of the clustering with the silhouette values method of Kaufman and Rousseeuw (1987). [29, 30] The technical details of our clustering algorithm are currently in the process of a patent investigation.

We produce a correlation matrix by computing the Pearson correlation coefficient between the time series data available for any two houses. Where a period is missing in any house, this is omitted from the time series vector. From this, a dissimilarity matrix is derived and used as input to the clustering algorithm with k = 3 clusters, as there are three phases in the data.

As an illustration of how the correlation coefficient is calculated between houses, we show a voltage time series plot in Fig 2. The houses with voltages represented by the green and red lines are highly correlated, with a Pearson correlation coefficient of 0.81. The house with voltage represented by the blue line is uncorrelated with the other two, with Pearson correlation coefficients of -0.83 and -0.70. In the final clustering, the algorithm places the “green” and “red” houses in one cluster and the “blue” in another.

Fig 2. Voltage time series plot.

Fig 2

In a dissimilarity matrix, houses within the same cluster are more similar, while houses in different clusters have their dissimilarity index maximised.

We tested the above method with 68 houses connected to two transformers in a suburban electricity network setting. The exact allocation was provided by the network operator after an audit at each house connection point. Our method correctly allocates 64 of the houses to the putative correct (un-ordered) phase.

We show a diagram of the location of the houses, with blue crosses representing the two tranformers, and red, green and black dots representing the locations of the houses attached to the transformers in Fig 3.

Fig 3. Locations of transformers and houses in suburb.

Fig 3

Note that in this paper, we calculate the error rate based on the best ordering of the prediction data, out of the six possible orderings. For instance, in the following confusion matrix, we would assess that 14 + 6 + 9 = 29 out of 33 houses have been allocated correctly. This is the best of the six possible phase orderings—values from each row and column are chosen so that all rows and columns are used, and the sum of the values is maximized. Reference cluster 1 would be associated with prediction cluster 3, reference cluster 2 with prediction cluster 2, and reference cluster 3 with prediction cluster 1.

ReferencePrediction1231029216031401

In order to allocate the correct order of phases, with uncertain records we suggest that existing records be leveraged, and testing carried out on a few houses that are clearly uncorrelated and appear to be on different phases.

Transformer 1 has 33 houses attached, while Transformer 2 has 35 houses attached. The data is from 17 January to 23 April 2019 in the first group, and from 5 February to 26 July 2019 in the second group.

At a one minute aggregation level, there are 97,647 rows for Transformer 1 and 179,414 rows for Transformer 2. This corresponds to approximately 70-73% coverage of all minutes in the data.

We plot the correlation matrices for the data and in the following figures (using the corrplot package of [31]). We also show the silhouette plots for each group in Figs 4 and 5.

Fig 4. Transformer 1 clusters.

Fig 4

Silhouette plot.

Fig 5. Transformer 2 clusters.

Fig 5

Silhouette plot.

In the first, the clusters produced are of size 11, 7 and 15.

According to the phase allocation provided by the network operator, the houses 12, 29, 41, and 76 are allocated incorrectly. As houses 12 and 29 are firmly within clusters 3 and 2, these may well be record keeping errors. House 29 has other issues as the associated device is allocated to two adjacent addresses in the data. Houses 41 and 76 have lower silhouette values in the chart indicating lower confidence in the clustering.

Fig 6 shows three clear clusters (dark blue squares) representing the three power phases.

Fig 6. Correlation plot for Transformer 1 with houses reordered according to algorithm clustering.

Fig 6

To validate the accuracy of our algorithm, the predicted phases for each house was checked against the network operator’s records for which house was connected to which phase.

In the second, the clusters produced are of size 13, 13 and 9. The phase allocation agrees with the network operator’s allocation at all houses.

Fig 7 shows the Transformer 2 correlation matrix, reordered according to algorithm clustering.

Fig 7. Correlation plot for Transformer 2 with houses reordered according to algorithm clustering.

Fig 7

We note that the error rate for Transformer 1 is five houses whether the aggregation level is chosen to be two, five, 10, 15, 20, 30, 60 or even 120 minutes. For example, at two and five minute aggregation, in addition, house 62 is misclassified; and at 10 to 120 minute aggregation, house 52 is misclassified.

At aggregation levels of 20 minutes and above, the Transformer 2 clustering misclassifies many houses—the error rate is 10 to 11 houses.

We also experimented with taking subsets of hours; for example, using only the hours from 3 a.m. to 6 a.m. at various aggregation levels. This did not consistently improve the error rate across both transformers.

We checked the un-ordered error rate for various input sizes in two different ways. The data for the first transformer has approximately 67 days, while the second transformer houses cover 124 days.

First, we tested the data in a sequential form—that is, for each possible day length d ∈ {1, …, n} where n is the total number of days, we extracted all sequential rows of day length d from the data, and computed the average error rate for d.

Second, we tested the data in random form; for each possible number of days d as above, we chose ten random sequences from the data with the same number of rows as d days (that is, 1440 × d rows) and calculated the average error rate of the clusterings obtained using these sequences.

The results are shown in Figs 8, 9, 10 and 11 below. For transformer 1, for both sequential and random testing, the average error rate is between 4 and 5 houses. For transformer 2, for sequential testing, the error rate is zero for at least 65 days of data and for random testing the error rate for zero for at least 4 days of data. For transformer 2 with sequential testing, there is a general downward trend, with an error rate of 9.5 with one day, decreasing as more days are added.

Fig 8. Transformer 1 error rate plot—Sequential day selection.

Fig 8

Fig 9. Transformer 2 error rate plot—Sequential day selection.

Fig 9

Fig 10. Transformer 1 error rate plot—Random day selection.

Fig 10

Fig 11. Transformer 2 error rate plot—Random day selection.

Fig 11

Discussion

Remotely detecting the phase of houses on an electricity grid minimises the likelihood of loss of power to HMED users. Our phase detection algorithm correctly determined the phase of 64 of the 68 houses upon which it was tested. Of the four incorrectly determined houses, two were found to be almost certainly a record keeping error on the part of the network operator. While further testing on larger datasets is required, these early indications of performance represent over 95% accuracy. The method is promising, given that the data underpinning the algorithm (high frequency sub-metered household consumption data) will soon be ubiquitously available to network operators through smart metering or installation of network sensing devices. This research advances prior phase detection algorithms which offer similarly high accuracy, but require transformer level energy use data [25, 26] which is not typically publicly available, and can present data interpolation issues due to the need to align timestamps on transformer and smart meter data [25].

Benefits of algorithm and phase detection: The ability to accurately and remotely determine the phase of a house has several direct benefits for network operators, and for users of HMEDs and other digital health technologies reliant upon uninterrupted electricity. These benefits include: improved ability to confidently forecast energy interruptions to energy vulnerable and energy dependent customers (e.g. those with HMEDs), minimise accidental disconnections and avoid fines of $20,000 (for network operators if they fail to provide at least four business days’ written notice of a planned interruption to the electricity supply of a vulnerable customer [21]). An accidental disconnection resulting in loss of life from an energy-dependent customer would have profound negative economic and reputational consequences for a network operator. Additionally, having complete and accurate information of dwellings’ phases within an energy grid, correlated with a register of home medical device customers, location and demographic information could assist in emergency planning by improved prediction of likely hospital admissions during a large scale network outage due to both medical device failure and heat/cold stress vulnerability among elderly demographics.

Benefits of monitoring hardware: Both network operators and HMED users additionally stand to benefit through the deployment of behind-the-meter technology necessary for phase detection. Behind-the-meter monitoring of energy consumption at high frequency allows for the creation of energy use visualisations and improved energy use feedback information. Real-time feedback on energy use is credited with improving awareness of energy use in the home [32] and improving understanding of the relative contributors to household energy bills and reduced energy bills [33]. Electricity vulnerable and electricity dependent customers are likely to be non-standard electricity users and may benefit from a greater understanding of the factors affecting their energy consumption. Further, network operators who presently lack real time system state information beyond the bulk-substation level will benefit from the improved demand response offered by broadscale sub-metering at the household level [34].

Collaborations towards better digital health outcomes

Advances in most digital health technologies (DHTs) are contingent upon access to stable and reliable electricity supply for powering HMED devices and charging other eHealth and mHealth devices. In developed countries this access is taken for granted. It has been well documented that this access, when removed either by planned outages [18], accident or by extreme weather or natural disasters [12, 17], imposes significant stress on vulnerable individuals.

We close with some recommendations for jurisdictions without detailed records of HMED users:

  1. Designers of DHTs should consider better communicating the consequences of interruptions of energy supply to users, including contingency plans, and websites/phone numbers to register their devices with network operators.

  2. Network operators, DHT manufacturers, and those who distribute or hire DHTs (e.g. hospitals) should collaborate more closely in the development of a formal register of HMEDs and other digital health deployments which are electricity-critical. This register should be available and editable by energy utilities, energy networks, DHT manufacturers and other necessary stakeholders (e.g. hospitals, doctors), thereby improving information delivery to network operators about the number, type and location of HMEDs that are deployed. This information could be fed into phase detection algorithms to further lower the likelihood of accidental disconnection. Consideration of personal data management and confidentiality are necessary here; however, moving the onus of registration with the network operator or energy utility from user to those who distribute or deploy HMEDs (e.g. hospitals, doctors etc) may increase the accuracy of location-based information on HMED deployment.

  3. Further work is required to increase the accuracy of phase detection, to improve certainty related to power interruptions. In order to improve the accuracy of the clustering algorithm, more phase identification data should be obtained, and a procedure developed to output a “confidence threshold” for correct phase identification, while using other information such as distance from the transformer and voltage at each house, together with testing different temporal aggregation levels and time slices of the day. When this threshold has been developed, in order to obtain a perfect phase identification, it will be necessary to test only a few houses attached to the transformer, such as representatives from each cluster, and houses that fall below this threshold. Since the data of this paper was collected, the resolution of the voltage data collected by the Power Analyzer device has improved from 1 V to 0.1 V. As Wang et al [22] noted, more granular voltage time series led to higher phase identification accuracy and we would also expect that this more accurate voltage data would improve accuracy.

In concluding, we argue that because continuation of advances in DHT are contingent upon reliable electricity supply, future work in digital health should consider power use needs beyond individual devices, and seek collaborations with researchers engaged in energy network management and emergency preparedness. To these ends, this paper has provided a proof of concept for a phase detection with tangible benefits to energy network operators, at home medical device users, digital health researchers and those engaged in emergency preparedness.

Supporting information

S1 Data

(DOCX)

Data Availability

The data repository files are available at https://doi.org/10.14264/uql.2020.802.

Funding Statement

This research was funded by the University of Queensland, Advance Queensland AQPTP01216-17RD1) (Queensland Government) and Redback Technologies. Authors RB, SS, MG, SV, NH all received funding in the form of salaries from the University of Queensland. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

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Decision Letter 0

Talib Al-Ameri

25 Feb 2020

PONE-D-20-02498

Keeping the Power on to Home Medical Devices

PLOS ONE

Dear Dr Bean,

Thank you for submitting your manuscript to PLOS ONE. After careful consideration, we feel that it has merit but does not fully meet PLOS ONE’s publication criteria as it currently stands. Therefore, we invite you to submit a revised version of the manuscript that addresses the points raised during the review process.

We would appreciate receiving your revised manuscript by Apr 10 2020 11:59PM. When you are ready to submit your revision, log on to https://www.editorialmanager.com/pone/ and select the 'Submissions Needing Revision' folder to locate your manuscript file.

If you would like to make changes to your financial disclosure, please include your updated statement in your cover letter.

To enhance the reproducibility of your results, we recommend that if applicable you deposit your laboratory protocols in protocols.io, where a protocol can be assigned its own identifier (DOI) such that it can be cited independently in the future. For instructions see: http://journals.plos.org/plosone/s/submission-guidelines#loc-laboratory-protocols

Please include the following items when submitting your revised manuscript:

  • A rebuttal letter that responds to each point raised by the academic editor and reviewer(s). This letter should be uploaded as separate file and labeled 'Response to Reviewers'.

  • A marked-up copy of your manuscript that highlights changes made to the original version. This file should be uploaded as separate file and labeled 'Revised Manuscript with Track Changes'.

  • An unmarked version of your revised paper without tracked changes. This file should be uploaded as separate file and labeled 'Manuscript'.

Please note while forming your response, if your article is accepted, you may have the opportunity to make the peer review history publicly available. The record will include editor decision letters (with reviews) and your responses to reviewer comments. If eligible, we will contact you to opt in or out.

We look forward to receiving your revised manuscript.

Kind regards,

Talib Al-Ameri, Ph.D

Academic Editor

PLOS ONE

Journal Requirements:

When submitting your revision, we need you to address these additional requirements:

1. Please ensure that your manuscript meets PLOS ONE's style requirements, including those for file naming. The PLOS ONE style templates can be found at http://www.plosone.org/attachments/PLOSOne_formatting_sample_main_body.pdf and http://www.plosone.org/attachments/PLOSOne_formatting_sample_title_authors_affiliations.pdf

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"No response"

  1. Please provide an amended Funding Statement that declares *all* the funding or sources of support received during this specific study (whether external or internal to your organization) as detailed online in our guide for authors at http://journals.plos.org/plosone/s/submit-now.  

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Please include your amended statements within your cover letter; we will change the online submission form on your behalf.

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Please complete your Competing Interests on the online submission form to state any Competing Interests. If you have no competing interests, please state "The authors have declared that no competing interests exist.", as detailed online in our guide for authors at http://journals.plos.org/plosone/s/submit-now

This information should be included in your cover letter; we will change the online submission form on your behalf.

4. We note that you have stated that you will provide repository information for your data at acceptance. Should your manuscript be accepted for publication, we will hold it until you provide the relevant accession numbers or DOIs necessary to access your data. If you wish to make changes to your Data Availability statement, please describe these changes in your cover letter and we will update your Data Availability statement to reflect the information you provide.

5. Please ensure that you refer to Figures 3, 5, 6, 7, 8, 9 in your text as, if accepted, production will need this reference to link the reader to the figure.

[Note: HTML markup is below. Please do not edit.]

Reviewers' comments:

Reviewer's Responses to Questions

Comments to the Author

1. Is the manuscript technically sound, and do the data support the conclusions?

The manuscript must describe a technically sound piece of scientific research with data that supports the conclusions. Experiments must have been conducted rigorously, with appropriate controls, replication, and sample sizes. The conclusions must be drawn appropriately based on the data presented.

Reviewer #1: No

Reviewer #2: Yes

Reviewer #3: Partly

**********

2. Has the statistical analysis been performed appropriately and rigorously?

Reviewer #1: N/A

Reviewer #2: I Don't Know

Reviewer #3: I Don't Know

**********

3. Have the authors made all data underlying the findings in their manuscript fully available?

The PLOS Data policy requires authors to make all data underlying the findings described in their manuscript fully available without restriction, with rare exception (please refer to the Data Availability Statement in the manuscript PDF file). The data should be provided as part of the manuscript or its supporting information, or deposited to a public repository. For example, in addition to summary statistics, the data points behind means, medians and variance measures should be available. If there are restrictions on publicly sharing data—e.g. participant privacy or use of data from a third party—those must be specified.

Reviewer #1: No

Reviewer #2: Yes

Reviewer #3: No

**********

4. Is the manuscript presented in an intelligible fashion and written in standard English?

PLOS ONE does not copyedit accepted manuscripts, so the language in submitted articles must be clear, correct, and unambiguous. Any typographical or grammatical errors should be corrected at revision, so please note any specific errors here.

Reviewer #1: No

Reviewer #2: Yes

Reviewer #3: Yes

**********

5. Review Comments to the Author

Please use the space provided to explain your answers to the questions above. You may also include additional comments for the author, including concerns about dual publication, research ethics, or publication ethics. (Please upload your review as an attachment if it exceeds 20,000 characters)

Reviewer #1: The novelty of this paper if any have not been significant. Substantial scientific aspects are missing in the paper such as the design of the proposed algorithm and hardware of the system. My recommendation is the paper is not suitable to publish in PLOS ONE (rejected).

Reviewer #2: This article addressed the power supply issue regarding home medical devices which has practical values. The work can be of certain reference in the area. I would like to recommend consider it for acceptance after further improvement.

Here are some of my impression about the work:

1. The present study appears some what too engineering which needs fruther in-depth improvement especially on fundamental parts.

2. Some earlier literatures on mobile health care are needed.

3. Originality of the curent work is not very clear. Power is a necessity and tremendous devices are available for such needs.

4. Adding some more basic innovative theoretical strategies will enhance curent work.

5. Unique feature of current energy supply perhaps can still be distinguished with existing one.

Reviewer #3: The authors present what appears to be a very novel idea with useful application. However, the development and operation of the phase algorithm, at least as it's written here is seems vague. In general, a more thorough presentation of the algorithm and analysis in reference to the actual operator measurements are needed. Please include some calculations and/or code on how, for example the error rates and plots were obtained. Figures 2 and 4 should be clearer/labeled better.

It would be most convincing to provide a map of the houses sampled, where the algorithm's phase is displayed, as well as the actual phase based on operator records. Authors should provide a copy of the operator records, perhaps as supplemental data.

**********

6. PLOS authors have the option to publish the peer review history of their article (what does this mean?). If published, this will include your full peer review and any attached files.

If you choose “no”, your identity will remain anonymous but your review may still be made public.

Do you want your identity to be public for this peer review? For information about this choice, including consent withdrawal, please see our Privacy Policy.

Reviewer #1: No

Reviewer #2: No

Reviewer #3: No

[NOTE: If reviewer comments were submitted as an attachment file, they will be attached to this email and accessible via the submission site. Please log into your account, locate the manuscript record, and check for the action link "View Attachments". If this link does not appear, there are no attachment files to be viewed.]

While revising your submission, please upload your figure files to the Preflight Analysis and Conversion Engine (PACE) digital diagnostic tool, https://pacev2.apexcovantage.com/. PACE helps ensure that figures meet PLOS requirements. To use PACE, you must first register as a user. Registration is free. Then, login and navigate to the UPLOAD tab, where you will find detailed instructions on how to use the tool. If you encounter any issues or have any questions when using PACE, please email us at figures@plos.org. Please note that Supporting Information files do not need this step.

Decision Letter 1

Talib Al-Ameri

25 May 2020

PONE-D-20-02498R1

Keeping the power on to home medical devices

PLOS ONE

Dear Dr. Bean,

Thank you for submitting your manuscript to PLOS ONE. After careful consideration, we feel that it has merit but does not fully meet PLOS ONE’s publication criteria as it currently stands. Therefore, we invite you to submit a revised version of the manuscript that addresses the points raised during the review process.

Please submit your revised manuscript by Jul 09 2020 11:59PM. If you will need more time than this to complete your revisions, please reply to this message or contact the journal office at plosone@plos.org. When you're ready to submit your revision, log on to https://www.editorialmanager.com/pone/ and select the 'Submissions Needing Revision' folder to locate your manuscript file.

Please include the following items when submitting your revised manuscript:

  • A rebuttal letter that responds to each point raised by the academic editor and reviewer(s). You should upload this letter as a separate file labeled 'Response to Reviewers'.

  • A marked-up copy of your manuscript that highlights changes made to the original version. You should upload this as a separate file labeled 'Revised Manuscript with Track Changes'.

  • An unmarked version of your revised paper without tracked changes. You should upload this as a separate file labeled 'Manuscript'.

If you would like to make changes to your financial disclosure, please include your updated statement in your cover letter. Guidelines for resubmitting your figure files are available below the reviewer comments at the end of this letter.

If applicable, we recommend that you deposit your laboratory protocols in protocols.io to enhance the reproducibility of your results. Protocols.io assigns your protocol its own identifier (DOI) so that it can be cited independently in the future. For instructions see: http://journals.plos.org/plosone/s/submission-guidelines#loc-laboratory-protocols

We look forward to receiving your revised manuscript.

Kind regards,

Talib Al-Ameri, Ph.D

Academic Editor

PLOS ONE

[Note: HTML markup is below. Please do not edit.]

Reviewers' comments:

Reviewer's Responses to Questions

Comments to the Author

1. If the authors have adequately addressed your comments raised in a previous round of review and you feel that this manuscript is now acceptable for publication, you may indicate that here to bypass the “Comments to the Author” section, enter your conflict of interest statement in the “Confidential to Editor” section, and submit your "Accept" recommendation.

Reviewer #1: (No Response)

Reviewer #2: All comments have been addressed

Reviewer #3: All comments have been addressed

**********

2. Is the manuscript technically sound, and do the data support the conclusions?

The manuscript must describe a technically sound piece of scientific research with data that supports the conclusions. Experiments must have been conducted rigorously, with appropriate controls, replication, and sample sizes. The conclusions must be drawn appropriately based on the data presented.

Reviewer #1: No

Reviewer #2: Partly

Reviewer #3: (No Response)

**********

3. Has the statistical analysis been performed appropriately and rigorously?

Reviewer #1: No

Reviewer #2: N/A

Reviewer #3: (No Response)

**********

4. Have the authors made all data underlying the findings in their manuscript fully available?

The PLOS Data policy requires authors to make all data underlying the findings described in their manuscript fully available without restriction, with rare exception (please refer to the Data Availability Statement in the manuscript PDF file). The data should be provided as part of the manuscript or its supporting information, or deposited to a public repository. For example, in addition to summary statistics, the data points behind means, medians and variance measures should be available. If there are restrictions on publicly sharing data—e.g. participant privacy or use of data from a third party—those must be specified.

Reviewer #1: No

Reviewer #2: Yes

Reviewer #3: (No Response)

**********

5. Is the manuscript presented in an intelligible fashion and written in standard English?

PLOS ONE does not copyedit accepted manuscripts, so the language in submitted articles must be clear, correct, and unambiguous. Any typographical or grammatical errors should be corrected at revision, so please note any specific errors here.

Reviewer #1: No

Reviewer #2: Yes

Reviewer #3: (No Response)

**********

6. Review Comments to the Author

Please use the space provided to explain your answers to the questions above. You may also include additional comments for the author, including concerns about dual publication, research ethics, or publication ethics. (Please upload your review as an attachment if it exceeds 20,000 characters)

Reviewer #1: (No Response)

Reviewer #2: The revised article has partially addressed the comments. A main concern is that originality can still be strengthened to fullfil the quanlity standard of PLoS ONE as could as possible. Anyway, I recommend accept the article for publication.

Reviewer #3: (No Response)

**********

7. PLOS authors have the option to publish the peer review history of their article (what does this mean?). If published, this will include your full peer review and any attached files.

If you choose “no”, your identity will remain anonymous but your review may still be made public.

Do you want your identity to be public for this peer review? For information about this choice, including consent withdrawal, please see our Privacy Policy.

Reviewer #1: No

Reviewer #2: No

Reviewer #3: No

[NOTE: If reviewer comments were submitted as an attachment file, they will be attached to this email and accessible via the submission site. Please log into your account, locate the manuscript record, and check for the action link "View Attachments". If this link does not appear, there are no attachment files.]

While revising your submission, please upload your figure files to the Preflight Analysis and Conversion Engine (PACE) digital diagnostic tool, https://pacev2.apexcovantage.com/. PACE helps ensure that figures meet PLOS requirements. To use PACE, you must first register as a user. Registration is free. Then, login and navigate to the UPLOAD tab, where you will find detailed instructions on how to use the tool. If you encounter any issues or have any questions when using PACE, please email PLOS at figures@plos.org. Please note that Supporting Information files do not need this step.

PLoS One. 2020 Jul 9;15(7):e0235068. doi: 10.1371/journal.pone.0235068.r004

Author response to Decision Letter 1


31 May 2020

Response to Reviewer #1 concerns in new "Response to Reviewers" letter - there is no new detail in reviewer comments, so we cannot do anything. We have asked the editor for a suggestion on what to do.

From response:

Reviewer #1 is actually incorrectly stating that details about the hardware (and in fact the algorithm) are missing as we have stated which commercial hardware we are using and we have disclosed how the algorithm works (on pages 6-8) just not a full disclosure and this is because there is a patent pending – there are a number of pages of detail. What would the editor recommend we do to address a factually incorrect comment from reviewer #1?

Attachment

Submitted filename: hmed-response-to-comments-1-jun-2020.docx

Decision Letter 2

Talib Al-Ameri

9 Jun 2020

Keeping the power on to home medical devices

PONE-D-20-02498R2

Dear Dr. Bean,

We’re pleased to inform you that your manuscript has been judged scientifically suitable for publication and will be formally accepted for publication once it meets all outstanding technical requirements.

Within one week, you’ll receive an e-mail detailing the required amendments. When these have been addressed, you’ll receive a formal acceptance letter and your manuscript will be scheduled for publication.

An invoice for payment will follow shortly after the formal acceptance. To ensure an efficient process, please log into Editorial Manager at http://www.editorialmanager.com/pone/, click the 'Update My Information' link at the top of the page, and double check that your user information is up-to-date. If you have any billing related questions, please contact our Author Billing department directly at authorbilling@plos.org.

If your institution or institutions have a press office, please notify them about your upcoming paper to help maximize its impact. If they’ll be preparing press materials, please inform our press team as soon as possible -- no later than 48 hours after receiving the formal acceptance. Your manuscript will remain under strict press embargo until 2 pm Eastern Time on the date of publication. For more information, please contact onepress@plos.org.

Kind regards,

Talib Al-Ameri, Ph.D

Academic Editor

PLOS ONE

Additional Editor Comments (optional):

Reviewers' comments:

Reviewer's Responses to Questions

Comments to the Author

1. If the authors have adequately addressed your comments raised in a previous round of review and you feel that this manuscript is now acceptable for publication, you may indicate that here to bypass the “Comments to the Author” section, enter your conflict of interest statement in the “Confidential to Editor” section, and submit your "Accept" recommendation.

Reviewer #1: All comments have been addressed

**********

2. Is the manuscript technically sound, and do the data support the conclusions?

The manuscript must describe a technically sound piece of scientific research with data that supports the conclusions. Experiments must have been conducted rigorously, with appropriate controls, replication, and sample sizes. The conclusions must be drawn appropriately based on the data presented.

Reviewer #1: Yes

**********

3. Has the statistical analysis been performed appropriately and rigorously?

Reviewer #1: Yes

**********

4. Have the authors made all data underlying the findings in their manuscript fully available?

The PLOS Data policy requires authors to make all data underlying the findings described in their manuscript fully available without restriction, with rare exception (please refer to the Data Availability Statement in the manuscript PDF file). The data should be provided as part of the manuscript or its supporting information, or deposited to a public repository. For example, in addition to summary statistics, the data points behind means, medians and variance measures should be available. If there are restrictions on publicly sharing data—e.g. participant privacy or use of data from a third party—those must be specified.

Reviewer #1: Yes

**********

5. Is the manuscript presented in an intelligible fashion and written in standard English?

PLOS ONE does not copyedit accepted manuscripts, so the language in submitted articles must be clear, correct, and unambiguous. Any typographical or grammatical errors should be corrected at revision, so please note any specific errors here.

Reviewer #1: Yes

**********

6. Review Comments to the Author

Please use the space provided to explain your answers to the questions above. You may also include additional comments for the author, including concerns about dual publication, research ethics, or publication ethics. (Please upload your review as an attachment if it exceeds 20,000 characters)

Reviewer #1: According to the intellectual property where the authors could not present more details about their work. I have no further comments and I recommend accepting the paper.

**********

7. PLOS authors have the option to publish the peer review history of their article (what does this mean?). If published, this will include your full peer review and any attached files.

If you choose “no”, your identity will remain anonymous but your review may still be made public.

Do you want your identity to be public for this peer review? For information about this choice, including consent withdrawal, please see our Privacy Policy.

Reviewer #1: Yes: Sadik Kamel Gharghan

Acceptance letter

Talib Al-Ameri

18 Jun 2020

PONE-D-20-02498R2

Keeping the power on to home medical devices

Dear Dr. Bean:

I'm pleased to inform you that your manuscript has been deemed suitable for publication in PLOS ONE. Congratulations! Your manuscript is now with our production department.

If your institution or institutions have a press office, please let them know about your upcoming paper now to help maximize its impact. If they'll be preparing press materials, please inform our press team within the next 48 hours. Your manuscript will remain under strict press embargo until 2 pm Eastern Time on the date of publication. For more information please contact onepress@plos.org.

If we can help with anything else, please email us at plosone@plos.org.

Thank you for submitting your work to PLOS ONE and supporting open access.

Kind regards,

PLOS ONE Editorial Office Staff

on behalf of

Dr. Talib Al-Ameri

Academic Editor

PLOS ONE

Associated Data

    This section collects any data citations, data availability statements, or supplementary materials included in this article.

    Supplementary Materials

    S1 Data

    (DOCX)

    Attachment

    Submitted filename: hmed-response-to-comments-10-apr-2020.docx

    Attachment

    Submitted filename: hmed-response-to-comments-1-jun-2020.docx

    Data Availability Statement

    The data repository files are available at https://doi.org/10.14264/uql.2020.802.


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