Figure 3.

Amyloid deposits in/around small endoneurial blood vessels in the left sural nerve of a 70-year old patient with immunoglobulin light chain amyloidosis. (A) White light microscopy of Congo red stained section, showing pink-stained thickening of vascular walls in a nerve fasciculus. These thickened vascular walls also stained positive for lambda light chains (not shown). (B,C) Enlargement of the framed area of the top panel, (B) viewed with white light, (C) viewed with polarized light, showing green/yellow birefringence of the Congo red positive vascular walls, proving the amyloid nature of these light chain deposits.