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. 2020 Jun 15;25(12):2763. doi: 10.3390/molecules25122763

Table 1.

Inhibition of lung cancer growth by pyrimethamine.

Cell Line DX2 Level GI50 (µM) 1
Pyrimethamine Taxol
H460 high 0.01 0.02
A549
HCC-1359
HCC-366		 moderate 0.8
14.3
22.3		 0.03
0.08
0.05
WI-26
H2087		 low >100
>100		 0.04
0.03

1 GI50 values are average of three independent experiments.