Skip to main content
. 2020 Jun 19;12(6):572. doi: 10.3390/pharmaceutics12060572

Table 4.

Effect of lipids to surfactant ratio on particle size, polydispersity index and zeta potential of NLC placebos (mean ± SD, n = 3).

Formulation Composition (%w/v) O-NLC-200 O-NLC
Precirol® ATO 5 3 4.5
Oleic acid 1 1.5
Tween® 80 2 2
Poloxamer 188 0.25 0.25
Glycerin 2.25 2.25
Water Up to 10 mL Up to 10 mL
PS (nm) 142.3 ± 3.9 226.0 ± 11.2
PDI 0.38 ± 0.01 0.60 ± 0.05
ZP (mV) −27.1 ± 1.7 −27.8 ± 0.5