Table 1.
Fifteen common secreted proteins by both R273H or R175H mutant p53 isoforms expressed in AsPC-1 cells and identified by using high-resolution SWATH-MS technology (p < 0.05).
| Accession Name | Entry | Protein Names | Gene | Fold Change versus Mock (FC) R273H R175H |
|---|---|---|---|---|
| IBP1_HUMAN | P08833 | Insulin-like growth factor-binding protein 1 | IGFBP1 | 4.49 3.03 |
| EPCR_HUMAN | Q9UNN8 | Endothelial protein C receptor | PROCR | 2.42 1.49 |
| TIMP1_HUMAN | P01033 | Metalloproteinase inhibitor 1 | TIMP1 | 2.18 1.30 |
| DCD_HUMAN | P81605 | Dermcidin | DCD | 1.94 1.37 |
| EZRI_HUMAN | P15311 | Ezrin | EZR | 1.82 2.48 |
| SAP_HUMAN | P07602 | Prosaposin | PSAP | 1.64 1.42 |
| VIME_HUMAN | P08670 | Vimentin | VIM | 1.47 2.32 |
| CSTN1_HUMAN | O94985 | Calsyntenin-1 | CLSTN1 | 1.43 2.51 |
| TAD2B_HUMAN | Q86TJ2 | Transcriptional adapter 2-beta | TADA2B | 1.39 1.37 |
| COF1_HUMAN | P23528 | Cofilin-1 | CFL1 | 1.35 1.52 |
| H4_HUMAN | P62805 | Histone H4 | HIST1H4A | 0.54 0.76 |
| H31_HUMAN | P68431 | Histone H3.1 | HIST1H3A | 0.43 0.46 |
| H32_HUMAN | Q71DI3 | Histone H3.2 | HIST2H3A | 0.41 0.40 |
| H2AV_HUMAN | Q71UI9 | Histone H2A.V | H2AFV | 0.33 0.45 |
| H2A2A_HUMAN | Q6FI13 | Histone H2A type 2-A | HIST2H2AA3 | 0.32 0.45 |