Table 2.
Annual rate of weight change pre and post the time of the switch (T0) to integrase strand transfer inhibitor (INSTI). For the non-INSTI group T0 was randomly assigned, assuming that the weight change was constant over the study period.
| Weight Change in kg/Year | All Patients * (N = 66) |
Female ** (N = 33) |
Male ** (N = 33) |
|---|---|---|---|
|
Pre-T0
(p-value) |
+0.47 (0.14–0.77) (0.006) |
+0.52 (0.08–0.95) (0.020) |
+0.42 (−0.06–0.91) (0.126) |
|
Post-T0
(p-value) |
+0.77 (0.44–1.10) (<0.0001) |
+0.97 (0.54–1.41) (<0.0001) |
+0.57 (0.09–1.06) (0.086) |
|
Pre-post Difference
(p-value) |
+0.30 (−0.16–0.77) (0.200) |
+0.46 (−0.16–1.07) (0.141) |
+0.15 (−0.54–0.84) (0.660) |
* Adjusted for age, sex and weight at baseline; ** adjusted for age and weight at baseline.