Identified Features Segregated Functional SFPQ Binding to Regulate Transcriptional Elongation of Long Genes
(A) Violin plots for FC-FC values of all expressed genes ≥30 kb, which were classified according to the identified SFPQ target intron criteria. Numbers in brackets shows intron counts in long genes (≥100 kb).
(B) Flowchart for long gene classification results by intron length and SFPQ target intron criteria. Genes for which pre-mRNA lengths ≥100 kb were classified into four groups: genes with strong-target introns (Genes w/Strong-Tgt), genes with weak-target introns (Genes w/Weak-Tgt), genes with non-target introns (Genes w/Non-Tgt), and genes without long introns (Genes w/o Long-Intron).
(C) Violin plots for fold changes (si-Sfpq/si-Cont) of classified long genes.
See also Figures S1 and S4 and Table S3.