Table 2.

DEGs continuous upregulating during the oncogenesis and metastasis of osteosarcoma

Gene symbol	Full name	GO BP ID	KEGG pathway
HLA-DRA	Major histocompatibility complex, class II, DR alpha	GO:0002478, GO:0019884, GO:0019886, GO:0048002, GO:0002495, GO:0002504, GO:0019882, GO:0060333, GO:0002429, GO:0071346, GO:0002768, GO:0034341, GO:0050852, GO:0002503, GO:0050851, GO:0002399, GO:0002501, GO:0002396	hsa04940, hsa05310, hsa05330, hsa05332, hsa05150, hsa05322, hsa04672, hsa05140, hsa04612, hsa04145, hsa05320, hsa05416, hsa05323, hsa05152, hsa04640, hsa05321, hsa04514, hsa04658, hsa04659, hsa05145, hsa05166, hsa05164, hsa05169
VAMP8	Vesicle Associated Membrane Protein 8	GO:0002478, GO:0019884, GO:0048002, GO:0019882, GO:0043312, GO:0002283, GO:0042119, GO:0002446, GO:0002697, GO:0002696, GO:0050867, GO:0002699, GO:0043304, GO:0033006, GO:0042590	/
A2M	Alpha-2-Macroglobulin	GO:0002697	hsa04610
SPARCL1	SPARC Like 1	/	/
HLA-DQA1	Major Histocompatibility Complex, Class II, DQ Alpha 1	GO:0002478, GO:0019884, GO:0019886, GO:0048002, GO:0002495, GO:0002504, GO:0019882, GO:0060333, GO:0002429, GO:0071346, GO:0002768, GO:0034341, GO:0050852, GO:0050851	hsa04940, hsa05310, hsa05330, hsa05332, hsa05150, hsa05322, hsa04672, hsa05140, hsa04612, hsa04145, hsa05320, hsa05416, hsa05323, hsa05152, hsa04640, hsa05321, hsa04514, hsa04658, hsa04659, hsa05145, hsa05166, hsa05164, hsa05169
APOC1	Apolipoprotein C1	GO:0043062, GO:0051346, GO:0060627, GO:0030100	/
AQP1	Aquaporin 1	GO:0015669, GO:0015701, GO:0046677, GO:0030185, GO:0006979, GO:0015670, GO:0048545, GO:0042476, GO:0042542, GO:0097237	hsa04964

/: no significant related GO BP or KEGG pathway term