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. 2020 Jun 3;21(9):575–586. doi: 10.2217/pgs-2020-0013

Figure 1.  . Study overview.

Figure 1.  

Schematic overview of the workflow for the ADME NGS panel sequencing. Composition of ADME NGS target genes displayed as Phase I, Phase I enzymes (n = 50); Phase II, Phase II enzymes (n = 38); and transporters (n = 60). For further details see Figures 2–4.

1 KGP: 1000 Genome Project; ADME: Absorption, distribution, metabolism and excretion; ExAC: Exome Aggregation Consortium; HWE: Hardy–Weinberg equilibrium; MAF: Minor allele frequency; Mind: Missingness per individual; NGS: Next-generation sequencing.