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. 2020 Jul 16;15(7):e0236532. doi: 10.1371/journal.pone.0236532

Correction: The second national tuberculosis prevalence survey in Vietnam

Hai Viet Nguyen, Edine W Tiemersma, Hoa Binh Nguyen, Frank G J Cobelens, Alyssa Finlay, Philippe Glaziou, Cu Huy Dao, Veriko Mirtskhulava, Hung Van Nguyen, Huyen T T Pham, Ngoc T T Khieu, Petra de Haas, Nam Hoang Do, Phan Do Nguyen, Cong Van Cung, Nhung Viet Nguyen
PMCID: PMC7365399  PMID: 32673361

In Table 1, the data and footnotes use an outdated analysis and do not correctly describe the contents of the table. Please see the correct Table 1 here.

Table 1. Classification of bacteriologically confirmed cases according to expert panel decision.

Xpert result a Culture result b Chest X-ray c TB treatment history d Number of cases
MTB detected MTB Growth Any Any 130 e
MTB not detected MTB Growth Abnormal Any 48
MTB detected No growth Abnormal No history 34
MTB detected No growth Abnormal < 2 years 2
MTB detected No growth Abnormal > 2 years 3
MTB detected Contaminated/missing/NTM Abnormal No history 4
MTB detected Contaminated/missing/NTM Abnormal < 2 years 0
MTB detected Contaminated/missing/NTM Abnormal > 2 years 0
Total number 221

MTB: Mycobacterium tuberculosis; NTM: Nontuberculous mycobacteria

a Combined result of two Xpert tests on different sputum sample (M1 and M1b). Does include participants with one (n = 55) and two (n = 118) Xpert results of MTB detected

b Final culture result, which is the MGIT result unless the MGIT culture was contaminated and the LJ culture result was either no growth or MTB+, then the LJ result was taken (n = 1)

c Final expert panel conclusion, abnormal meaning chest X-ray with any abnormality suggesting active TB disease

d Treatment history as reported by the participant in the in-depth interview

e Five of these patients were on TB treatment at the time of the survey, and five reported to have TB treatment history within two years preceding the survey.

In Table 2 and Table 4, the headings Rural and Remote are swapped in the fifteenth and sixteenth rows. The fifteenth row should be Remote and the sixteenth row should be Rural. Please see the correct Table 2 and Table 4 here.

Table 2. Screening outcomes of the survey, by sex, age, area, and region.

Total screened participants Total screening positive Interview a screening positive only Chest X-ray screening positive only Both interview and chest X-ray positive
No. % p-value No. % p-value No. % p-value No. % p-value
Total 61,163 4,738 7.7 2,207 3.6 1,849 3.0 682 1.1
Sex <0.001 <0.001 <0.001 <0.001
    Male 27,150 2,842 10.5 1,272 4.7 1,088 4.0 482 1.8
    Female 34,613 1,896 5.5 935 2.7 761 2.2 200 0.6
Age group <0.001b <0.001b <0.001b <0.001b
    15–24 6,542 135 2.1 <0.001c 99 1.5 <0.001c 27 0.4 <0.001c 9 0.1 <0.001c
    25–34 10,191 379 3.7 <0.001c 253 2.5 <0.001c 84 0.8 <0.001c 42 0.4 <0.001c
    35–44 11,508 577 5.0 <0.001c 360 3.1 0.004c 160 1.4 <0.001c 57 0.5 <0.001c
    45–54 13,289 1,074 8.1 0.045c 565 4.3 <0.001c 370 2.8 0.110c 139 1.1 0.468c
    55–64 11,143 1,193 10.7 <0.001c 529 4.8 <0.001c 494 4.4 <0.001c 170 1.5 <0.001c
    ≥ 65 9,090 1,380 15.2 <0.001c 401 4.4 <0.001c 714 7.9 <0.001c 265 2.9 <0.001c
Area 0.383 <0.001 <0.001 <0.001
    Urban 18,656 1,415 7.6 0.595c 487 2.6 <0.001c 710 3.8 <0.001c 218 1.2 0.314c
    Remote 15,882 1,216 7.7 0.935c 692 4.4 <0.001c 403 2.5 <0.001c 121 0.8 <0.001c
    Rural 27,225 2,107 7.7 0.537c 1,028 3.8 0.016c 736 2.7 <0.001c 343 1.3 0.001c
Region <0.001 <0.001 <0.001 <0.001
    North 25,575 1,917 7.5 <0.001c 1,094 4.3 <0.001c 639 2.5 <0.001c 184 0.7 <0.001c
    Central 13,525 1,216 9.0 0.168c 531 3.9 <0.001c 391 2.9 0.428c 294 2.2 <0.001c
    South 22,663 1,605 7.1 <0.001c 582 2.6 0.012c 819 3.6 <0.001c 204 0.9 <0.001c

No: number of participants with such characteristics

a Including those who reported TB symptoms and/or TB treatment history, defined as follows:

TB symptoms: cough for 2 weeks or more, or cough of any duration in pregnant women.

Treatment history: currently on TB treatment or reporting TB treatment in the 2 years preceding the survey

b p-value for trend, obtained by rank-sum test

c p-value for the difference between this age group/ area/ region with other groups combined, obtained by Pearson’s chi-squared test

Table 4. Estimated prevalence of pulmonary tuberculosis in Vietnam, overall and by sex, age, area and region.

Smear-positive TB Xpert-positive TB Bacteriologically confirmed TB
Number of participants No. of cases Crude prevalence
(per 100,000)
n (95% CI)
Weighted prevalence
(per 100,000)a
n (95% CI)
p-value No. of cases Crude prevalence
(per 100,000)
n (95% CI)
Weighted prevalence
(per 100,000)a
n (95% CI)
p-value No. of cases Crude prevalence
(per 100,000)
n (95% CI)
Weighted prevalence
(per 100,000)a
n (95% CI)
p-value
Total 61,763 50 81 (61–107) 79 (55–115) 173 280 (241–325) 235 (187–296) 221 358 (314–408) 322 (260–399)
Sex 0.004 <0.001 <0.001
    Male 27,150 34 125 (89–175) 118 (78–180) 138 508 (430–600) 390 (309–491) 175 645 (556–747) 522 (420–648)
    Female 34,613 16 46 (28–75) 42 (23–79) 35 101 (72–141) 89 (60–134) 46 133 (100–177) 133 (89–198)
Age group <0.001b <0.001b 0.001b
    15–24 6,542 0 0 0 4 61 (23–163) 49 (19–127) <0.001c 4 61 (23–163) 63 (18–226) 0.007c
    25–34 10,191 9 88 (46–170) 109 (55–218) 0.218c 13 128 (74–220) 142 (76–264) 0.051c 17 167 (104–268) 203 (114–360) 0.049c
    35–44 11,508 8 70 (35–139) 69 (35–134) 0.637c 21 182 (119–280) 185 (111–308) 0.263c 31 269 (190–383) 287 (180–454) 0.556c
    45–54 13,289 15 113 (68–187) 123 (72–211) 0.056c 42 316 (233–427) 344 (239–496) 0.034c 50 376 (285–496) 423 (300–597) 0.113c
    55–64 11,143 13 117 (68–201) 130 (68–251) 0.116c 52 466 (356–612) 505 (365–698) <0.001c 62 556 (434–713) 618 (463–823) <0.001c
    ≥ 65 9,090 5 55 (23–132) 55 (18–167) 0.515c 41 451 (332–612) 446 (317–629) <0.001c 57 627 (484–812) 689 (511–930) <0.001c
Area 0.034 0.004 0.024
    Urban 18,656 27 145 (99–211) 140 (86–228) 0.008c 75 402 (321–504) 342 (252–463) 0.008c 90 482 (393–593) 445 (327–604) 0.020c
    Remote 15,882 13 82 (48–141) 76 (44–133) 0.893c 44 277 (206–372) 247 (148–414) 0.818c 52 327 (250–429) 309 (181–526) 0.852c
    Rural 27,225 10 37 (20–68) 37 (15–93) 0.032c 54 198 (152–259) 152 (108–215) 0.003c 79 290 (233–362) 241 (182–572) 0.027c
Region 0.129 0.159 0.297
    North 25,575 10 39 (21–73) 44 (22–86) 0.131c 49 192 (145–253) 168 (105–267) 0.102c 70 274 (217–346) 262 (180–380) 0.173c
    central 13,525 14 104 (61–175) 92 (48–176) 0.044c 42 311 (230–420) 253 (152–423) 0.067c 49 362 (274–479) 316 (181–552) 0.939c
    South 22,663 26 115 (78–168) 106 (62–182) 0.640c 82 362 (292–449) 289 (216–385) 0.749c 102 450 (371–546) 380 (287–504) 0.163c

No: number; CI: confidence interval; N/A: Not available

a Weighted prevalence: estimated prevalence after missing data imputation, inverse probability weighting and post-stratification (see more in the Data collection and analysis section)

b p-value for trend, obtain by Wald test

c p-value for the difference between this age group/area/region with other groups combined, obtained with logit regression

Reference

  • 1.Nguyen HV, Tiemersma EW, Nguyen HB, Cobelens FGJ, Finlay A, Glaziou P, et al. (2020) The second national tuberculosis prevalence survey in Vietnam. PLoS ONE 15(4): e0232142 10.1371/journal.pone.0232142 [DOI] [PMC free article] [PubMed] [Google Scholar]

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