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. 2020 Jul 9;10(18):8211–8226. doi: 10.7150/thno.44419

Figure 6.

Figure 6

Validation of circ-133 promotes the migration ability of normoxic CRC cells directly. OE circ-133, OE NC, si-circ-133 and si-NC were transfected into CRC cells, respectively. (A) High intension imaging cell analysis showed that circ-133 promotes the migration of normoxic CRC cells (n=3). (B) Quantitative analysis of A, (n=3). (C) Validation of circ-133 mediated normoxic CRC cell migration by transwell assay (n=3). (D) Quantitative analysis of C, (n=3). (E) Wound healing assay demonstrated circ-133 enhance the migration ability of normoxic CRC cells (n=3). (F) Immunofluorescence assay was used to detect E-cadherin membrane distribution in each treatment group, (n=3).